Mrs. Aggiebrad94 - class of '91 is currently kicking cancer's a@$. She's been in partial remission for nearly 3 years. We've been cruising along with good scan results all that time - nothing new and nothing grew.

However, the blood work the last two times has started to become troubling.

After being in the low 40's for years, the CA 15-3 (tumor marker) rose to 180 in January and 540 this week.

The liver enzymes are also significantly higher than normal.

Something is going on and I'd like to enlist the power of texags to help. She'll be having weekly blood draws for the next few weeks, a liver ultrasound and they (MD-Anderson) will set up a meet with a Hepatologist. MDA asked that we stop using all of the supplements we've been using for the past 4 years (which I believe is one of the key reasons she's done so well).

Any advice or anyone have any experience with a spiking liver enzyme during chemo?

My friend who is 10 years out from chemo/radiation for breast cancer has had liver enzyme issues ever since. They can't figure out why.

Not helpful info for you I'm sure but will pray for your wife!

Wow! That's interesting. Do you know if they take any supplements to help the liver?

Thank you for the prayers. It's my number 1 reason for her doing so well.

Tumor markers rising like that, to me (oncology nurse), is concerning.

What are her liver numbers? What was her prior treatment?

aggiebrad94 said:

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Wow! That's interesting. Do you know if they take any supplements to help the liver?

Thank you for the prayers. It's my number 1 reason for her doing so well.

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Mostly she tries to eat clean and not over indulge with the adult beverages. It's been a rollercoaster with the enzymes though and they can't make much sense of it. Every few months she goes in for bloodwork to check it out.

Aries said:

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Tumor markers rising like that, to me (oncology nurse), is concerning.

What are her liver numbers? What was her prior treatment?

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AST has been in the high 20's and rose to 62 in January and 124 last week
ALT has been in high teens, low 20's and rose to 78 in January and 167 last week
Alkaline Phosphate has been around 100 for a couple of years and went up to 107 and triggered the high
Albium is normal at 4.4

Not sure what other blood tests relate to the liver

Glucose is also high and has been for multiple quarterly tests

bump for the nurse

Best wishes and prayers for her health!