Fewer consequences w/Humidity using Closed cell foam &/or Rockwool.
Office would need at least a window/thru-wall AC or one w/heat aka PTAC, some require 220v.
This avenue would not vent to outside humidity.
I would require an office window.
LG window ACs have served us well.
Sizing experience w/LG 11.3 SEER
Min. windowed rooms use 450sf/ton
40-50% windowed rooms use 200sf/ton (perhaps more SF if shaded 100% or North wall)
Gotta draw since me got no grammar MasterArch '76