List of major HCL trials registered through NIH

998 Views | 8 Replies | Last: 5 yr ago by Zobel
SMM48
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AG
?1
BiochemAg97
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AG
Some of those dates don't make sense. The first one from Apr 20 to Apr 21, but it is looking at prevention in healthcare workers and the endpoint is a measure of who gets sick? That isn't going to happen in one day.


Others are 5 months. seems like you would be able to enroll enough patients quickly and the observable outcomes seem more like something that should happen within a month.

CHEN Ag 2019
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AG
I could be wrong but I read the numbers as years.
BiochemAg97
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Jtayers23 said:

I could be wrong but I read the numbers as years.
That would make sense. A year long study of healthcare professionals given drugs to prevent infection makes sense.

However, a year long study to compare disease progression with treatment doesn't seem necessary or helpful. Although I guess it is a good idea to follow for a year to see any side effects of the treatment that manifest later.
DadHammer
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If people are testing positive and you give the HCQ and Zpac treatment you will know in two weeks or less if it works. I don't understand the issue here.

We are in a crisis where time matters immensely. If it only helps 5% of patients that's an improvement.

If HCQ or something like it can reduce infection level if taken early we should be using it. Not waiting until on your death bed.

I don't need a dang year long government study because liberals want to hurt the president, this is about saving lives and our jobs so we can put food on the table and a roof over our kids heads. Side effects are so small it's not worth discussing. If you don't want to take them then don't but don't try to block others from using it.
CowboyGirl
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Why are none of the hydroxychloroquine/z-pack trials including zinc? I thought that was part of what was successful in stopping the replication of the virus.
Zobel
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The issue is it is very difficult to tell if the drug is actually working on a disease where you expect 99% of people to get it to recover without any intervention.

Especially when you consider that the probability for any particular person who acquires the disease to die is much less than 1%.

This has been turned into a political issue, when it really isn't one.
cisgenderedAggie
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Study completion dates are estimated and not something to be overly concerned on. At the earliest, it's going to be the projected date of the last per protocol follow up for the last subject in the study. Without knowing the study protocol l, you can't know how long they are following subjects for safety/resolution.

No one is going to wait a year to release results from these studies.
RGLAG85
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k2aggie07 said:

The issue is it is very difficult to tell if the drug is actually working on a disease where you expect 99% of people to get it to recover without any intervention.

Especially when you consider that the probability for any particular person who acquires the disease to die is much less than 1%.

This has been turned into a political issue, when it really isn't one.
There is more to this virus than death. They are using these drugs on patients that they've seen similar symptoms who had mild to severe consequences, even death, and are having results that seem miraculous.
Zobel
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Also -- doing these studies isn't preventing doctors from prescribing these drugs. Doctors use drugs off label all the time.
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