how many infections would be required to result in 200k dead by July?

1,603 Views | 13 Replies | Last: 5 yr ago by culdeus
cone
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AG
assuming current levels of social distancing and especially paranoia amongst the older, non-working cohort?

in NYC as of last night:

327 deaths under 64

32793 cases under 64

1% CFR

we can assume that not everyone under the age of 64 who is positive for the disease is not represented in the case load, especially if the 18-44 year old rate of hospitalization is 9%. it's likely that there are 1.5 - 2x as many unreported cases in that cohort.

so assume a 0.5% IFR for those 64 and older (this isn't meant for strict scrutiny)

i also assume that if anyone is abiding by severe social distancing when possible, it's the 65+ population. the virus will still get in that cohort, but at a more lower speed. that is to say, between now and July, this is the segment that would be most likely to stay the f home, simply out of self-preservation and paranoia.

so how many people would need to be infected to reach 200k dead?

200k / 0.005 = 40 MM

say that the older population does get infiltrated (but not fully) - pare back the total number of infected required to 75% of 40 MM = 30 MM

do you think 30 MM infections between now and July with the peak of deaths (which lag infections) happening in the next two weeks is plausible?

or is the key to the math that Americans of working age (who haven't yet died in NYC) will eventually die and the mortality rate in that cohort is significantly higher than what they are seeing in Italy (due to us being obese and diabetic at a younger age)?

is the short term problem with America not the older people (who heeded the advice and removed themselves from society) but the younger people who are also extremely vulnerable to this disease?
I Am A Critic
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It will take 10-15MM infected.
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Jbob04
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AG
I don't see anyway we hit these numbers. Seems crazy at this point
cone
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that's a really high IFR

so either our current infection numbers are off the chart huge and everything is baked in

OR

we are going to have a much higher IFR amongst our younger cohort than other nations
Bruce Almighty
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I've seen it floated on here a few times to take the number of deaths and multiply by 800 to approximate the number of infections. I don't know where that number comes from, but that would equal 160M people, or about half the country.
BDub3
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AG
Divide the deaths by CFR in decimal form is the easy way.
HotardAg07
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AG
I understand that the numbers sound crazy, but remember that on March 1st we only had 75 confirmed cases and one person had died from the coronavirus in the US and today we are over 190,000 confirmed and 4,000 dead.

Yesterday's official death toll was 912, up from 558 the day before. Where does that peak end up? Birx shows it somewhere between 1,200 and 3,500 daily. In order to get 200,000 deaths in 90 days, we'd have to average 2,222 deaths per day for that period. It doesn't seem impossible for that to happen. We are already fairly close to the 1,111 deaths per day needed to get 100,000 deaths by July.


I find it uninteresting to talk about death rate anymore, because that implies some knowledge of how many people are infected and we just aren't close to knowing. Most people's guesses says more about their underlying biases than their scientific knowledge, unless you're someone like Infection Ag 11. Additionally, it seems pretty clear to me that death rate has more to do with:

1. Age distribution of the infected -- biased older will be higher death rate, biased younger will be lower death rate
2. Ability of the hospital system to accomodate -- In Italy, where their hospital system is overwhelmed, death rates are higher at the same age groups compared to other countries who had outbreaks but did not overwhelm their hospital systems.


(from 8 days ago)
Shaun Shaikh '07
HumpitPuryear
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AG
"on March 1st we only had 75 confirmed cases and one person had died from the coronavirus in the US"

These numbers are severely limited by ability to actually test. We have a ramp in infections at the same time we are having a ramp in testing. It's impossible to know how much of the overall ramp can be attributed to which factor. We could easily have had deaths in early March that were COVID but not confirmed because of lack of testing to confirm. Same is true of confirmed cases.
cone
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i'm just curious how it spreads to 15+ million Americans in 4-6 weeks given the lockdown

what's the mechanism for spread? what's the venue?

unless of course 10 million Americans already have it
I Am A Critic
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cone said:

i'm just curious how it spreads to 15+ million Americans in 4-6 weeks given the lockdown

what's the mechanism for spread? what's the venue?

unless of course 10 million Americans already have it
There is no lockdown. Look at what people were doing two weeks ago and how freely they were moving and how freely moving many still are. As long at there is a subset of the population who ignores whats's going, believes it only happens to older people, believes that maintaining the economy is more important than preserving life, believes it's no worse than the flu etc, there will be a chance for this to spread.
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ETFan
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Long incubation period, plenty of people are still out and about (groceries, etc) and/or going to their essential job during the week.

cone
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but that subset who thinks it ain't no big thing would certainly not be the vulnerable subset

so the extent of the infection to get to 200k dead in 4-6 weeks would have be to absolutely massive

or else it'd have to be more deadly to that younger more laissez faire cohort

and i have a hard time believing the vector that gets us to 20 MM cases in 4-6 weeks is a grocery trip
HotardAg07
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AG
cone said:

i'm just curious how it spreads to 15+ million Americans in 4-6 weeks given the lockdown

what's the mechanism for spread? what's the venue?

unless of course 10 million Americans already have it
1. We do NOT have a national lock down and the places doing shelter in place are not being universally observed. That's very clear.

2. Even if our shelter in place restrictions were perfectly followed, people are still congregating at grocery stores, health care workers are getting infected (I believe 20% of the confirmed infections in Italy are health care workers), and people doing essential services are interacting every day (note 15% of Police Officers in NYC are quarantining for CV).

3. Again, I don't find the infection rates and death rates to be a particularly enlightening conversation, because it says more about your biases than it says about hard science. However, trying to stay as close as possible to the science, our Infection Ag 11 estimates 0.5% death rate when all is said and done, including all the people with mild/no symptoms. To have 200,000 deaths, that would require 40,000,000 people infected.

We are at 190,000 CONFIRMED cases right now. However, this doesn't account for the fact that:
  • The number is a look into the past. Consider once someone is infected, it takes them 2-12 days to show symptoms (if they show them at all), then it takes some amount of days for those symptoms to rise to the level of needing a test, then it takes in some places 7-14 days to get test results after getting a test. We are looking at infections that happened 3+ weeks ago.
  • We are restricting testing in many places to only those who need to be hospitalized (~20% of cases)
  • There are people in the confirmed infected population today who may still yet die. There are only 7,500 cases in the US officially resolved.
  • Our case fatality rate snap shot as of today is 2.2% if you divide the total deaths by total CONFIRMED infected. If you were to use that to try to extrapolate how many CONFIRMED cases we would need to get to 200,000 deaths, it would be 9,000,000. We have been multiplying confirmed cases by 10x every 8 days in this country so far, with all of the limitations noted above. As this rate of growth, our testing cannot keep up, because we should be at a million cases by April 5th, but that would require daily rises in cases greater than our daily testing capability.However, if that were not a limitation, we would have 1,000,000 confirmed cases by April 5th and 10,000,000 confirmed cases by April 13th. If you say that it shouldn't be that dramatic, because our lockdown should have flattened the curve, then that still makes it seem feasible that we could have 10,000,000 confirmed cases by July.

  • I think the bottom line is that exponential growth is... really fast and hard to wrap our minds around. It was just March 11th, 3 weeks ago, when the Ivy League cancelled their season and everybody thought it was a ridiculous overreaction. Now, in hindsight, it seems very normal/expected/reasonable and like something that happened months ago. This has been moving so fast.
    cone
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    AG
    Quote:

    If you say that it shouldn't be that dramatic, because our lockdown should have flattened the curve, then that still makes it seem feasible that we could have 10,000,000 confirmed cases by July.
    but the death curves have it peaking within 2-4 weeks

    i get exponential growth, but i also get that humans won't run head long into a woodchipper

    the more the dead pile up, the more people will be too frightened to go outside (regardless of how initially invincible they see themselves as)

    that would also imply that we're reaching peak case load now, since deaths lag 2-4 weeks

    so we're already in the millions of cases required to hit the ~3k/day dead

    it just feels off, that's all. NYC right now has 45k cases. 8500 hospitalized. 1100 dead. but their per day case/count has decreased 6 days in a row from 3213 on 3/24 to 1241 yesterday.
    culdeus
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    AG
    I Am A Critic said:

    cone said:

    i'm just curious how it spreads to 15+ million Americans in 4-6 weeks given the lockdown

    what's the mechanism for spread? what's the venue?

    unless of course 10 million Americans already have it
    There is no lockdown. Look at what people were doing two weeks ago and how freely they were moving and how freely moving many still are. As long at there is a subset of the population who ignores whats's going, believes it only happens to older people, believes that maintaining the economy is more important than preserving life, believes it's no worse than the flu etc, there will be a chance for this to spread.


    I've seen plenty of YouTube models to say just 80% half assing it gets us to a sustainable death rate. That's with 20% yoloing.

    Sustainable death rate is nobody dying because there is no hospital to admit them.
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