Antibody test in Italy

2,656 Views | 12 Replies | Last: 5 yr ago by dr_boogs
HidalgoCounty
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Has this been discussed?
40 of 60 blood donors tested in one small Italian town were asymptomatically positive for having had or currently have covid-19.
And no...all 40 are not presymptomatic so let's not go there
The article is in Italian...just use translate.
https://www.ilcittadino.it/cronaca/2020/04/02/contagiati-senza-saperlo-all-avis-sono-ben-40-su-60/KYwVaGiHShP3odU4dY4zx3/index.html

dermdoc
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AG
I have been preaching that the antibody test is so much more important than the "test".
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
AgDoc03
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AG
Mayo hopes to have one available next week
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Matt Hooper
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AG
I am a medical moron. Can you give me a quick explanation of what this tells you and the benefit?
Thanks in advance.
Hooper Drives the Boat
Sq 17
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Not a dr but I have read Anti-Body test will reveal that a person had it
Right now if you had it got better and were basically asymptomatic a viral check would come back negative.
For plasma donation and for clearance to go about daily activities the you had it and got better is the test we need
jamey
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AG
The current test and results everyone is reporting are genetic tests of the actual virus meaning it's in your body at the time of sampling


An antibody test looks for your immune response to the virus

So of you arent sick X number of days later you're probably immune and can safely lick hand rails again
dr_boogs
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AG
Here's a brief rundown:

The body makes different types of antibodies, which are complex proteins made by specific cells of the immune system. They have various names based on structure and function, IgM, IgG, with more complexity built in to each type.

Antibodies circulate through the blood and tissues and due to their unique structure, bind/interact with the cell surface or virus capsule. Once the antibody (Ab) has bound to the pathogen, it signals other cells of the immune system to internalize the Ab-pathogen complex and destroy or sequester the pathogen, removing it from the tissue or circulation. It's a fascinating component of the immune system.

Related to the OP, antibodies can be acquired from other people through blood/plasma transfusions, an infant nursing a mother and having Ab transfer through milk, or by being exposed to the pathogen previously.

So the point of the OP is that one likely explanation for such a high % of the Italians in that town having antibodies to COVID but no symptoms is that they were exposed to COVID, experienced minor or no symptoms, and their bodies created Abs to the virus.
Snap E Tom
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jamey said:



So of you arent sick X number of days later you're probably immune and can safely lick hand rails again
That's funny because I just told my wife that I should have had the BCG vaccine as an infant, and I was about to go out and lick hand rails and kiss stray cats.

See y'all! I'm gonna go out and party again!
Matt Hooper
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AG
Thank you. Very helpful.
Hooper Drives the Boat
dermdoc
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dr_boogs said:

Here's a brief rundown:

The body makes different types of antibodies, which are complex proteins made by specific cells of the immune system. They have various names based on structure and function, IgM, IgG, with more complexity built in to each type.

Antibodies circulate through the blood and tissues and due to their unique structure, bind/interact with the cell surface or virus capsule. Once the antibody (Ab) has bound to the pathogen, it signals other cells of the immune system to internalize the Ab-pathogen complex and destroy or sequester the pathogen, removing it from the tissue or circulation. It's a fascinating component of the immune system.

Related to the OP, antibodies can be acquired from other people through blood/plasma transfusions, an infant nursing a mother and having Ab transfer through milk, or by being exposed to the pathogen previously.

So the point of the OP is that one likely explanation for such a high % of the Italians in that town having antibodies to COVID but no symptoms is that they were exposed to COVID, experienced minor or no symptoms, and their bodies created Abs to the virus.


I am impressed that you would have the patience to explain that.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
$3 Sack of Groceries
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AG
Antibody? No! Antipasti, si!

boulderaggie
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Excellent explanation. Even a caveman like me could understand it.
dr_boogs
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dermdoc said:

dr_boogs said:

Here's a brief rundown:

The body makes different types of antibodies, which are complex proteins made by specific cells of the immune system. They have various names based on structure and function, IgM, IgG, with more complexity built in to each type.

Antibodies circulate through the blood and tissues and due to their unique structure, bind/interact with the cell surface or virus capsule. Once the antibody (Ab) has bound to the pathogen, it signals other cells of the immune system to internalize the Ab-pathogen complex and destroy or sequester the pathogen, removing it from the tissue or circulation. It's a fascinating component of the immune system.

Related to the OP, antibodies can be acquired from other people through blood/plasma transfusions, an infant nursing a mother and having Ab transfer through milk, or by being exposed to the pathogen previously.

So the point of the OP is that one likely explanation for such a high % of the Italians in that town having antibodies to COVID but no symptoms is that they were exposed to COVID, experienced minor or no symptoms, and their bodies created Abs to the virus.


I am impressed that you would have the patience to explain that.


I practice at A&M's veterinary teaching hospital, run a research lab, and teach veterinary students for a living. It was right in my wheelhouse. Glad to help.
dr_boogs
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AG
boulderaggie said:

Excellent explanation. Even a caveman like me could understand it.


No problem, glad you found it helpful.
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