Covid-19 Re-Activation

4,004 Views | 20 Replies | Last: 5 yr ago by BlackGoldAg2011
Brad 98
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AG
I am starting to read where Japan and South Korea are starting to see instances of cleared cases getting the virus again. If this is a virus that can lay dormant in one cells, than should we get on life?
Ag00Ag
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AG
Link?
Brad 98
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AG
https://www.dailymail.co.uk/news/article-8192015/Fifty-one-recovered-coronavirus-patients-test-positive-South-Korea.html
Gordo14
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That would be awful if true. Hopefully the immune system is better equipped to fight back at least...
Ag00Ag
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AG
Thanks.

From the article

Quote:

in cases where patients produce a positive result twice, it is normally because of a test giving the wrong result, which happens one in five times.

Paul Hunter, an infectious diseases professor at the University of East Anglia, told MailOnline: 'I agree that these will not be reinfections but I do not think these will be reactivations.

'Personally I think the most likely explanation is that the clearance samples were false negative.'



certainly hope this is the case.
Pulmcrit_ag
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I highly recommend against reading sensationalist dailymail headlines. Best to avoid that site in its entirety.
Strongweasel97
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AG
Pulmcrit_ag said:

I highly recommend against reading sensationalist dailymail headlines. Best to avoid that site in its entirety.
This is worth a blue star and a blue star post.
Irwin M. Fletcher
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Pulmcrit_ag said:

I highly recommend against reading sensationalist dailymail headlines. Best to avoid that site in its entirety.
Totally agree, that article was very poor and Daily Mail is looking for clicks.
Aggie95
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AG
1) poor headline/article

2) if you can have the flu more than once, not sure why this would be any different...although not so soon after recovery

3) IF..IF, we ever find this ahole virus can infect individuals multiple times in short time frames then I would be sad to say we'd just have to scrap social distancing, go back to normal and just let the fittest survive.
Cancelled
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50 people in South Korea allegedly (by a click bait sensationalist rag) got sick again out of 275,000 recovered? I'll take those odds.
cbr
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AG
While it doesnt seem to be bearing out today here, if you believe public info, there was certainly a lot of anecdotal indications of this happening from china early on.
aggie_bryan
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AG
I'll have to go find it some data on this but I know I've heard of instances where "recovered" patients continue to test positive after they've recovered.

One of the Diamond Princess travelers who had Covid-19 was kept in quarantine long after he stopped showing symptoms due to the fact that he was continuing to show viral load in his bloodstream.

This is extremely concerning. If recovered individuals have the capability to continue to spread the virus after recovery, that would be a major MAJOR issue. Anybody else seen any of this reported elsewhere?
Cancelled
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One can only hope for more fear to come!
TRADUCTOR
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queso1 said:

One can only hope for more fear to come!
Include the 70yo's to scare the outliers. The >70 data is just like the medieval warming data manipulated to scare.
AgResearch
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AG
aggie_bryan said:

I'll have to go find it some data on this but I know I've heard of instances where "recovered" patients continue to test positive after they've recovered.

One of the Diamond Princess travelers who had Covid-19 was kept in quarantine long after he stopped showing symptoms due to the fact that he was continuing to show viral load in his bloodstream.

This is extremely concerning. If recovered individuals have the capability to continue to spread the virus after recovery, that would be a major MAJOR issue. Anybody else seen any of this reported elsewhere?
His nasal tested showed positive sheding for ~36 days.
BlackGoldAg2011
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AG
Any additional evidence for this type of thing? i ask because here is the scenario in our house

3/18 (5 days after our family began extreme social distancing):
myself and both kids all show fevers just shy of 101
I have a headache, a sore throat and mild shortness of breath and fatigue
3/19:
wife joins us with same symptoms
all fevers are in the low 101s
3/19-3/24:
all show fevers in the low to mid 101s
wife and i both complaining of shortness of breath, burning pain in lungs, headaches, body aches, and fatigue
3/25:
wife's fever clears but other symptoms continue
the rest of us maintain fevers in the 100.5-100.6 range
3/26:
wife's breathing gets so bad she goes to stand alone ER. gets checked out and a COVID test (is 48 hrs post fever at this point), is proscribed antibiotics for potential infection and sent home. test comes back negative 3 days later)
the rest of us have no change.
3/28 (day 11):
fist day fever free for the remaining 3 of us. SOB and lung burning continues
3/31 (day 14):
first day all symptom free so stop recording daily status

4/3:
i have a headache so bad i can hardly open my eyes. assume its bad allergies due to weather changing
4/5:
wife is feeling run down and feels hot so we check temps, we are at 102.4 and 102.5 kids are asleep so can't check them
4/7-4/8:
both have fatigue, SOB, my chest burning returns. Also mild abdominal cramping
all 4 have temps ranging in the 100.5-101.5 range

in all of this time we have gone nowhere. all groceries and mail coming in the house has been sanitized and packaging immediately thrown away so i have no idea how we could have possibly picked up anything new. due to the incubation period and the symptom list we kind of assumed we had it. if so this could add some credence to the idea that it can linger and/or come back. this is purely anecdotal and we don't have a confirmed test, but we have friends in NYC that mentioned they know of 5 people who "had it" and had it clear and come back. I have no idea if any of those cases are confirmed. Just wanted to throw this out there since it fit the story from the OP
Duncan Idaho
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Showing symptoms 5 days AFTER you started social distancing isnt unexpected. The asymptomatic phase can be as long as 14 days. Which is why this is such a nightmare.
Ag for Life
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AG
Pulmcrit_ag said:

I highly recommend against reading sensationalist dailymail headlines. Best to avoid that site in its entirety.

Yep, I'm pretty sure my computer has AIDS from clicking links to that site.
BlackGoldAg2011
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AG
Duncan Idaho said:

Showing symptoms 5 days AFTER you started social distancing isnt unexpected. The asymptomatic phase can be as long as 14 days. Which is why this is such a nightmare.
that's actually one of the main reasons we are thinking COVID is what we have. 5-6 day incubation rules out a lot of other viruses.
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BlackGoldAg2011
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AG
AstroAg17 said:

Dormancy should not be a thing with this coronavirus (or any coronavirus).

Viruses can stay dormant and be reactivated in 2 ways as far as I know:

1: They hide in neurons. Neurons aren't subject to the same level of surveillance from the immune system. Herpes viruses do this. They are hiding in your neurons until an opportunity arises for them to reinfect the surrounding area. That's why they pop up in the same area repeatedly.

2: They are retroviruses, which insert their genes into your genome. At that point it doesn't matter if your immune system clears the virus, because your cells will now produce virus when they try to produce their own proteins.

I am making a distinction between dormancy and being asymptomatic. Dormancy to me means that it's not actively replicating. Individuals can be symptomatic with COVID, asymptomatic, then symptomatic again if they have an acute infection, fail to completely clear it and then the viral load blows up again. I think that's the most likely explanation for the positive-negative-positive test results. They were infected the whole time but they were below the detectable level for the negative. It could also be testing error.
this was my thought to the most likely scenario as well. sure does suck being on day 23 of being sick though, i guess the respite in the middle was a nice break though to literally and figuratively catch our breaths.
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