What if having Covid-19 antibodies does not give you immunity?

3,632 Views | 28 Replies | Last: 5 yr ago by TXAggie2011
FrecklesDad
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AG
What do we do next?

I say we have to go back to living as close to normal as possible. Wear masks and practice good hygiene. Quarantine the sick and try not to get sick. What else can we do?
flown-the-coop
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You gp back to normal. People get sick, they get tested, they get the cocktail, they get better and go out again.

People have been getting sick a long time. People have been dying from getting sick a long time. People have gotten better from being sick due to medicine for a long time.

What's new here?
PJYoung
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AG
Test test test.

Testing is the key to coming out of this.
flown-the-coop
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Do we test everyone everyday until the end of time? If that's the plan, I am plowing all my money into Abbot.

Never understand what testing does long term. Short term I see some benefits. But if I test a nurse today, they are negative, they go to work, get exposed, get COVID, then in the succeeding 5-7 days continues to go to work, go home, hang with family, then I test them again a week later, they are now positive, I tell them to go home for 14 days.

But the damage was done. You have to see that testing is a tool, but not a solution at all.
Aggie95
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you go back to pre-covid and wait for herd immunity/vaccine....and the fittest survive.
cone
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and yet

where is the testing capacity?
Badace52
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FrecklesDad said:

What do we do next?

I say we have to go back to living as close to normal as possible. Wear masks and practice good hygiene. Quarantine the sick and try not to get sick. What else can we do?


It is not really about whether or not the antibodies will give you immunity. If you have the antibodies at a high enough titer (amount of antibodies in the body) you will have complete immunity to the current version of SARS-CoV-2.

If you have lower titers, you may not have complete immunity, but generally lower antibody titers mean when you do catch the illness again it will be much less intense than it would have been were you completely naieve to the virus.

The issues at hand are really two fold...

1. Will the virus mutate quickly and intensely enough that the virus has changed to where previous antibodies no longer provide immunity to the new version yearly (like the flu)?

2. How long will the antibodies made to SARS-CoV-2 last in the body and keep one immune before they would need a "booster shot" to keep their immunity?

The answer to both are unknown, but all evidence from the histories of similar viruses and lab studies on SARS-CoV-2 which have been trying to determine the stability of the viruses genetic information seem to point to the virus mutating slowly and being relatively stable, (similar to other known coronaviruses).

This means it is highly likely that those who have been infected with the virus (especially those who had a big immune response to it... a.k.a. the sicker patients) and then recovered will likely be immune to this virus.

Now for how long the immunity will last... This is not known either, but it is assumed it will be many, many years as it is with most other "cold" type viruses.



Tldr version:
This virus seems to change slowly and is unlikely to come back in a new version every year like the flu, and it is very likely that if you have this disease and recover you will be immune from it for a long time (several years, maybe decades).
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Dad
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AG
I don't think getting it again will be a problem and if we do get it again it will probably be like a cold.

My bigger concern is that maybe this was not an accident but a test run by China and they have bigger plans for the future. If China's numbers are real then they figured this virus out and did not share with the world or they created the virus and had a cure already ready that they did not share with the world. They could also be lying about their numbers and dit is doing just as much damage there as it did in other places.
California Ag 90
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aggie-beta said:

I don't think getting it again will be a problem and if we do get it again it will probably be like a cold.

My bigger concern is that maybe this was not an accident but a test run by China and they have bigger plans for the future. If China's numbers are real then they figured this virus out and did not share with the world or they created the virus and had a cure already ready that they did not share with the world. They could also be lying about their numbers and dit is doing just as much damage there as it did in other places.
it would be the most self destructive dumbass stunt in history.

they are in economic free fall. there is not a country in the world that isn't exploring how to get their supply chains disentangled from China. China has no where near the domestic demand to backfill its export markets, yet. they have over 200M still in poverty, in spite of their export driven success in building a middle class. their population is aging rapidly due to the decades of one-child policy, and their incentives to increase the birth rate have largely failed.

from an image perspective, the face-conscious Chinese culture is being assailed on a global scale, no matter how much PC policing tries to prevent it. you think human beings who are losing loved ones to this disease will pay attention to the PC efforts to deflect the justified rage at the PRC? they won't. China's carefully crafted image has taken a devastating hit.

China is ****ed. if they did this on purpose, they are idiots. it was not intentional - it was a catastrophic mistake either in food regulation or laboratory control. it has altered the course of world history, and irreparably damaged China.



We're from North California, and South Alabam
and little towns all around this land...
lunchbox
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Saw an article yesterday that the medical professionals that got sick and had to recover and then quarantine are starting to go back to the front lines. Will be interesting to see if we see reports of any of them getting sick again.
Morgan94
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California Ag 90 said:

aggie-beta said:

I don't think getting it again will be a problem and if we do get it again it will probably be like a cold.

My bigger concern is that maybe this was not an accident but a test run by China and they have bigger plans for the future. If China's numbers are real then they figured this virus out and did not share with the world or they created the virus and had a cure already ready that they did not share with the world. They could also be lying about their numbers and dit is doing just as much damage there as it did in other places.
it would the most self destructive dumbass stunt in history.

they are in economic free fall. there is not a country in the world that isn't exploring how to get their supply chains disentangled from China. China has no where near the domestic demand to backfill its export markets, yet. they have over 200M still in poverty, in spite of their export driven success in building a middle class. their population is aging rapidly due to the decades of one-child policy, and their incentives to increase the birth rate have largely failed.

from an image perspective, the face-conscious Chinese culture is being assailed on a global scale, no matter how much PC policing tries to prevent it. you think human beings who are losing loved ones to this disease will pay attention to the PC efforts to deflect the justified rage at the PRC? they won't. China's carefully crafted image has taken a devastating hit.

China is ****ed. if they did this on purpose, they are idiots. it was not intentional - it was a catastrophic mistake either in food regulation or laboratory control. it has altered the course of world history, and irreparably damaged China.




This. For those that think China did this on purpose, they are missing the broader point mentioned above. The Chinese economy is irreparably damaged from this.They are screwed...
HidalgoCounty
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People have been saying it's not like the flu, but I have a feeling we will come to find it is identical to the flu.
The flu before we had a vaccine and before we had any sort of natural immunity built up due to it being around so long.
dcbowers
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The reason that you have antibodies is that you have developed immunity to the virus. If you are not making antibodies, then you probably were not exposed to the virus or you did not survive the virus.

The unknowns include (1) whether the virus will mutate (answer: probably not much); (2) whether there will be sufficient titers and will body's production of antibodies is durable (unknown, but they should be around for at least a while).
dcbowers
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
flown-the-coop
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I have a terminology question and this is not meant to be political, but I am going to reference Trump. But the response does not need to invoke one side or another.

Trump was lambasted in the press for talking about antibiotics in regard to viruses. With the adage that viruses cannot be treated with antibiotics,

This thread is based on the body building "antibodies" to the virus. My question is simply why is it that the "antibiotics" due not treat a virus, but we need "antibodies" to fight the virus?

The terms are close enough where I can see the confusion, and I am sure I can google an answer, but there are also experience people on here who can answer the difference.
KidDoc
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flown-the-coop said:

You gp back to normal. People get sick, they get tested, they get the cocktail, they get better and go out again.

People have been getting sick a long time. People have been dying from getting sick a long time. People have gotten better from being sick due to medicine for a long time.

What's new here?
What's new here is a new virus. A virus that did not exist 4 months ago.

The proof & studies on long term immunity are pending because it is a NEW VIRUS. I think people really lose perspective that we are learning as we go because this is a BRAND NEW VIRUS to the planet. All the models and projections are just that, guessing and predictions.

It is annoying. It is frustrating, It is NEW and different. It sucks.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
flown-the-coop
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I get that KidDoc. My point is somewhat consistent with yours, said a different way. I agree it's different, it's new and yes it sucks, at the same time, we have dealt with these scenarios before, we develop resistance, treatments and vaccines, I think there is consensus that this is not "novel" enough to wipe out mankind.
KidDoc
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flown-the-coop said:

I get that KidDoc. My point is somewhat consistent with yours, said a different way. I agree it's different, it's new and yes it sucks, at the same time, we have dealt with these scenarios before, we develop resistance, treatments and vaccines, I think there is consensus that this is not "novel" enough to wipe out mankind.
Certainly not. We are strangely lucky as a species that this first modern pandemic jump from animal to human is actually a relatively mild virus. Hopefully this will encourage world & USA to take pandemic preparation and prevention a priority in the future as it is most certainly one of the most likely ways for the species to end. Think if ebola, SARS, MERS made a jump like this with high mortality and the R0 of COVID.

This is a warning. The wet markets of China need to stop. We need to take any novel virus jump very seriously and clamp down aggresively.

Not COVID related but the ways civilization end are likely: pandemic, AI, Asteroid hit, Volcano. We can plan for some of those things but world governments are caught up in day to day drama and largely ignore big picture issues which is what they should be focused on. Volcano is the one that I cannot think of any good prevention/solution but geophysics is way out of my wheel house.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
flown-the-coop
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Could not agree more. Any thoughts on my antibiotic vs antibody question?
Capitol Ag
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True. But we also have to get back to normal, sooner rather than later. Living scared isn't an answer either. At some point, the public will need to know that they will just have to live with the risk until a vaccine can be made. Until then, we just wash hands, wear a mask if you choose to (don't make it mandatory, but that my opinion), we get back to living. At what point is the "cure" worse than the disease is my question.
Capitol Ag
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KidDoc said:

flown-the-coop said:

I get that KidDoc. My point is somewhat consistent with yours, said a different way. I agree it's different, it's new and yes it sucks, at the same time, we have dealt with these scenarios before, we develop resistance, treatments and vaccines, I think there is consensus that this is not "novel" enough to wipe out mankind.
Certainly not. We are strangely lucky as a species that this first modern pandemic jump from animal to human is actually a relatively mild virus. Hopefully this will encourage world & USA to take pandemic preparation and prevention a priority in the future as it is most certainly one of the most likely ways for the species to end. Think if ebola, SARS, MERS made a jump like this with high mortality and the R0 of COVID.

This is a warning. The wet markets of China need to stop. We need to take any novel virus jump very seriously and clamp down aggresively.

Not COVID related but the ways civilization end are likely: pandemic, AI, Asteroid hit, Volcano. We can plan for some of those things but world governments are caught up in day to day drama and largely ignore big picture issues which is what they should be focused on. Volcano is the one that I cannot think of any good prevention/solution but geophysics is way out of my wheel house.


Great points all.
Dad
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California Ag 90 said:

aggie-beta said:

I don't think getting it again will be a problem and if we do get it again it will probably be like a cold.

My bigger concern is that maybe this was not an accident but a test run by China and they have bigger plans for the future. If China's numbers are real then they figured this virus out and did not share with the world or they created the virus and had a cure already ready that they did not share with the world. They could also be lying about their numbers and dit is doing just as much damage there as it did in other places.
it would the most self destructive dumbass stunt in history.

they are in economic free fall. there is not a country in the world that isn't exploring how to get their supply chains disentangled from China. China has no where near the domestic demand to backfill its export markets, yet. they have over 200M still in poverty, in spite of their export driven success in building a middle class. their population is aging rapidly due to the decades of one-child policy, and their incentives to increase the birth rate have largely failed.

from an image perspective, the face-conscious Chinese culture is being assailed on a global scale, no matter how much PC policing tries to prevent it. you think human beings who are losing loved ones to this disease will pay attention to the PC efforts to deflect the justified rage at the PRC? they won't. China's carefully crafted image has taken a devastating hit.

China is ****ed. if they did this on purpose, they are idiots. it was not intentional - it was a catastrophic mistake either in food regulation or laboratory control. it has altered the course of world history, and irreparably damaged China.





That's good to hear. If they are suffering from this they deserve every bit of it. If it happened in the wet market they knew there was a risk allowing those markets and didn't care enough to stop it.
FrecklesDad
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This pandemic just makes the Book of Revelations in the Bible become more real than ever. It describes events and scourges that are hard to wrap your head around, but this pandemic makes it much easier to understand.
Seven Costanza
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flown-the-coop said:

I have a terminology question and this is not meant to be political, but I am going to reference Trump. But the response does not need to invoke one side or another.

Trump was lambasted in the press for talking about antibiotics in regard to viruses. With the adage that viruses cannot be treated with antibiotics,

This thread is based on the body building "antibodies" to the virus. My question is simply why is it that the "antibiotics" due not treat a virus, but we need "antibodies" to fight the virus?

The terms are close enough where I can see the confusion, and I am sure I can google an answer, but there are also experience people on here who can answer the difference.
Antibiotics and Antibodies are two completely different things. Antibiotics are drugs that, for the most part, kill or inhibit bacteria. Antibodies are products of your immune system that work to "kill" bacteria, viruses, allergens, foreign bodies, parasites, etc.
Dad
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AG
Seven Costanza said:

flown-the-coop said:

I have a terminology question and this is not meant to be political, but I am going to reference Trump. But the response does not need to invoke one side or another.

Trump was lambasted in the press for talking about antibiotics in regard to viruses. With the adage that viruses cannot be treated with antibiotics,

This thread is based on the body building "antibodies" to the virus. My question is simply why is it that the "antibiotics" due not treat a virus, but we need "antibodies" to fight the virus?

The terms are close enough where I can see the confusion, and I am sure I can google an answer, but there are also experience people on here who can answer the difference.
Antibiotics and Antibodies are two completely different things. Antibiotics are drugs that, for the most part, kill or inhibit bacteria. Antibodies are products of your immune system that work to "kill" bacteria, viruses, allergens, foreign bodies, parasites, etc.

We all know antibiotics are mostly prescribed to deal with bacteria but they are trying several antibiotics to treat this virus. I guess will find out down the road if it helped any.
Seven Costanza
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I understand. His question was regarding the basic difference between an antibiotic and antibody, given the similarity of the names.
cbr
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KidDoc said:

flown-the-coop said:

You gp back to normal. People get sick, they get tested, they get the cocktail, they get better and go out again.

People have been getting sick a long time. People have been dying from getting sick a long time. People have gotten better from being sick due to medicine for a long time.

What's new here?
What's new here is a new virus. A virus that did not exist 4 months ago.

The proof & studies on long term immunity are pending because it is a NEW VIRUS. I think people really lose perspective that we are learning as we go because this is a BRAND NEW VIRUS to the planet. All the models and projections are just that, guessing and predictions.

It is annoying. It is frustrating, It is NEW and different. It sucks.
Ive been *****ing about lack of accurate or useful data. This has been running 5 months now. Somebody ****ing knows exactly whether most 'recovered' carriers have immunity, and somebody ****ing knows a lot of other things about this cirus by now. Yet the infirmation is being wittheld. Why?
flown-the-coop
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Seven Costanza said:

Antibiotics and Antibodies are two completely different things. Antibiotics are drugs that, for the most part, kill or inhibit bacteria. Antibodies are products of your immune system that work to "kill" bacteria, viruses, allergens, foreign bodies, parasites, etc.
That would have been my assumption. There is a point of how many people can confuse the terminology.

It would be interesting to know why the terminology is not simpler.

Antibody is a natural (or artificially instigated) immune response.

Antibiotic is a drug for bacterial infections.

Antivirals are for viral infections?

Why are antibiotics just not called antibacterial?
KidDoc
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cbr said:

KidDoc said:

flown-the-coop said:

You gp back to normal. People get sick, they get tested, they get the cocktail, they get better and go out again.

People have been getting sick a long time. People have been dying from getting sick a long time. People have gotten better from being sick due to medicine for a long time.

What's new here?
What's new here is a new virus. A virus that did not exist 4 months ago.

The proof & studies on long term immunity are pending because it is a NEW VIRUS. I think people really lose perspective that we are learning as we go because this is a BRAND NEW VIRUS to the planet. All the models and projections are just that, guessing and predictions.

It is annoying. It is frustrating, It is NEW and different. It sucks.
Ive been *****ing about lack of accurate or useful data. This has been running 5 months now. Somebody ****ing knows exactly whether most 'recovered' carriers have immunity, and somebody ****ing knows a lot of other things about this cirus by now. Yet the infirmation is being wittheld. Why?
Because China. (IMO)
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Redassag94
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AG
You have an annual vaccine like the flu shot. It will protect most, others not and some will die. We live our lives as before and CV will not be the #1 cause of death every year... not even close. And it won't Be this year either.
TXAggie2011
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aggie-beta said:

My bigger concern is that maybe this was not an accident but a test run by China and they have bigger plans for the future.
The Community Party of China hangs its legitimacy on economic growth. Their promise to the masses is the ability to purchase a car, a smartphone, and go on a vacation to a foreign country.

China lies, but China isn't stupid. While people make mistakes, purposefully unleashing this on the world would be a mistake of such epic proportion its practically unfathomable.

And just a general Chinese foreign policy point: They're generally risk adverse for a country of their stature. They've become much bolder in recent years, but this wouldn't just be rocking the boat, its straight up dropping a nuclear bomb on it.


You can't prove a negative, but that just is not a theory I personally would get concerned about unless, somehow, someway, a modicum of evidence appears.


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