https://nymag.com/intelligencer/2020/04/we-still-dont-know-how-the-coronavirus-is-killing-us.html

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In a fantastic survey published April 17 ("How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes," by Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, and Catherine Matacic), Science magazine took a thorough, detailed tour of the ever-evolving state of understanding of the disease. "Despite the more than 1,000 papers now spilling into journals and onto preprint servers every week," Science concluded, "a clear picture is elusive, as the virus acts like no pathogen humanity has ever seen."

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The patient's chart appeared unremarkable at first glance. He took no medications and had no history of chronic conditions. He had been feeling fine, hanging out at home during the lockdown like the rest of the country, when suddenly, he had trouble talking and moving the right side of his body. Imaging showed a large blockage on the left side of his head. Oxley gasped when he got to the patient's age and covid-19 status: 44, positive.

The man was among several recent stroke patients in their 30s to 40s who were all infected with the coronavirus. The median age for that type of severe stroke is 74.

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As Oxley, an interventional neurologist, began the procedure to remove the clot, he observed something he had never seen before. On the monitors, the brain typically shows up as a tangle of black squiggles "like a can of spaghetti," he said that provide a map of blood vessels. A clot shows up as a blank spot. As he used a needlelike device to pull out the clot, he saw new clots forming in real-time around it.

"This is crazy," he remembers telling his boss.

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Complete Idiot said:

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I'm sorry, I think the wording is ridiculous click bait. "A ferocious rampage through the body, from brain to toes"? Cmon. I think this is a serious or deadly illness for many, many people but seems to have no impact for much larger number of people. I think that sentence, and a title like "we don't know how it is killing us", just causes a lot more fear than is warranted. And I lean to the take this more serious aisle I think, compared to others.

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I agree with you, but if you look, they were quoting the title of an article/study that was published and and a quote from it.

Complete Idiot said:

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I'm sorry, I think the wording is ridiculous click bait. "A ferocious rampage through the body, from brain to toes"? Cmon. I think this is a serious or deadly illness for many, many people but seems to have no impact for much larger number of people. I think that sentence, and a title like "we don't know how it is killing us", just causes a lot more fear than is warranted. And I lean to the take this more serious aisle I think, compared to others.

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The way they report the virus boarders on massive sensationalism. Granted, the media will always do this as it leads to clicks and site visits, as you point out. But it does a massive disservice and only feeds our fears rather than educating us about what we do know. To the vast majority of us, this virus will come and go and we will be fine. And to say we don't know how this kills the very few it does isn't entirely true at all. It's a very tricky little F'er no doubt and we are learning a lot as we go, but I wonder if the more important quest always has been WHO the virus tends to kill for the overall population. Obviously, doctors need to know how it kills to fight it and save the lives of those that it attacks so aggressively. But, for the population as a whole, the key is to know which demographics it does attack the most so that we can take the proper precautions in terms of who we should quarantine and stay away from to keep them safe. Again, the best approach, imo, is to quarantine the sick and those most at risk, not the healthy folks.

And, before someone chimes in to say "there are "perfectly healthy, younger people that have died from this", on the surface that may be correct. But those are major outliers and even in many (if not most) of those circumstances, there were some sort of underlying condition we either did not know about, or were just not reported about. Again, my skepticism alarm goes off every time they report about a younger person dying without any underlying condition given as it sure sounds like a great chance for the media to get clicks and create more sensationalism that results in unnecessary panic.

But we do know this. Maybe not the full details, but on this very board the docs who post here have been discussing the need to proactively treat for clotting factors for at least a month.

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What day is it?

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Today is Day. Yesterday was Day and tomorrow will be Day.