Avoiding Cytokine Storm - Dr. Tom Yadegar - None of His Patients Have Died

3,511 Views | 9 Replies | Last: 5 yr ago by RandyAg98
MaroonDontRun
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AG
I'm sure most that are interested have already seen how this doctor is treating patients but I thought I would post it on here just in case some of the docs have been too busy. To my knowledge Dr. Yadegar has not lost a Covid 19 patient yet.

Quote:

Speaking from Los Angeles on Tuesday, Dr. Tom Yadegar, a specialist in critical care medicine who has been treating COVID-19 patients, said he noticed several patients were deteriorating quickly and needed to be put on ventilators. He said he realized that he had to find out why these patients were experiencing sudden deterioration.

"This happened to me just like it's happened to every other doctor who is taking care of these patients and it was very alarming that I didn't understand what happened," said Yadegar, medical director of the intensive care unit at Providence Cedars-Sinai Tarzana Medical Center.

He said that prompted him to start researching what was happening to those COVID-19 patients. Yadegar explained that through his research he found out that "what was happening is a process called cytokine storm syndrome."

According to the National Cancer Institute (NCI), cytokine storm, which can occur as a result of infection, autoimmune conditions or diseases, is "a severe immune reaction in which the body releases too many cytokines into the blood too quickly."
"Cytokines play an important role in normal immune responses, but having a large amount of them released in the body all at once can be harmful," NCI explained.

On Tuesday, Yadegar explained that "in this syndrome, the immune system is activated you have intense inflammation and subsequently it leads to patients requiring mechanical ventilation."

He said once he figured out what the diagnosis was, he started doing more research to try and figure out "how do we look for it in a laboratory value so that we can find it before it happens because when it happens, it's almost too late."

He added that "it's very important to find these patients and prevent them from going on ventilators."

Yadegar said he came up with "a handful of lab tests" that he thought were useful "and we started ordering them on admission when the patients were presenting to the ER [emergency room] and then tracking them every few days and it was a very clear pattern that we learned."

He noted that it is not the case that every COVID-19 patient that is admitted to the hospital develops cytokine storm syndrome.

"You can predict on presentation who is going to be at risk for it and then if you follow certain markers and their clinical course you can actually tell who is going to develop it and, more importantly, you can intervene to prevent them from getting to that point where they need a ventilator," Yadegar said.

He said that as people's immune systems kick in, he has a better result by actually suppressing that person's immune system, which he said was "pretty counterintuitive."

TLDR: This doctor tests patients on admission and has developed ways to identify patients early on that are likely to experience Cytokine Storm in order to treat them properly.

Edit: Added the URL https://www.foxnews.com/media/california-doctor-develops-process-for-identifying-extreme-covid-19-cases-and-how-to-treat-them
RandyAg98
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AG
Makes sense that intervening before the Cytokine Storm might stop these guys from getting so bad. Some of the docs on here, particularly Marcus Aurelius, have been focusing on the Cytokine Storm for awhile now. This seems to back him up.
DTP02
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AG
Is there a link to where you got the excerpt? I want to pass on to someone.
Sq 17
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advancements like this are one of the few reasons to try and slow the spread , I hope this Dr is on to something that works for the Cytokine Storm patients
Tx-Ag2010
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AG
I'm curious if they are using (or will use) AI to optimize treatments based on patient age, sex, comorbidities, lab test results, etc. It seems like if you could upload enough raw data it could find links that are not openly apparent.
Gizzards
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AG
In the Covid 19 news cycle scheme, this is really not new information at this point. We have been trying plenty of things so far to combat this cytokine storm and checking markers of inflammation to help predict it. So far nothing has proven to consistently help, but several options are being used and studied.
Marcus Aurelius
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AG
Not to detract from OP post. But the COVID-19 "orderset" has been in place since mid March for most US hospitals. Includes CBC diff (for N/L ratio), ferritin, CRP, LFTS, renal function. IL-6 surges correlate with storm. IL-6 inhibitors anecdotally effective against this. Have seen it first hand. See my earlier posts re this. And Riley from NY. And InfectionAg. Sorry to forget him.
Infection_Ag11
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AG
I've been doing this since early March, trending certain labs and in certain scenarios administering treatments based on those labs continuing to rise.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
bmks270
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AG
Who is most at risk for this cytokines storm? Is it patients who are otherwise healthy that have this strong immune response? Or patients that have some other health dysfunction?
BLB_95
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AG
Marcus Aurelius said:

Not to detract from OP post. But the COVID-19 "orderset" has been in place since mid March for most US hospitals. Includes CBC diff (for N/L ratio), ferritin, CRP, LFTS, renal function. IL-6 surges correlate with storm. IL-6 inhibitors anecdotally effective against this. Have seen it first hand. See my earlier posts re this. And Riley from NY. And InfectionAg. Sorry to forget him.
When I read the OP I thought it sounded exactly what I have been reading in this forum for weeks.

It's almost like this Dr. read Texags and then presented all of this as his own work or at least the author of the article presents it that way.
RandyAg98
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AG
Just goes to show you that these doctors on the front lines, with their anecdotal experience, are at the forefront of more controlled research. Their initiative, fearlessness, and ingenuity are going to be what beats this thing.
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