Doctors thought on Remdesivir...

2,434 Views | 6 Replies | Last: 5 yr ago by Not a Bot
Aggie95
How long do you want to ignore this user?
AG
I know it's not quite a silver bullet but it has really positive results compared to others...two part question

1) if we currently had 20 million doses of Remdesivir available would you be less anxious about reopening? and would you go so far as a more expedited reopening?

2) If on Dec 1st we had 20 Million doses of Remdesivir and we knew early intervention was key (along with the understanding that ventilators were not the answer)....how many of the ~60k deaths would have been avoided? Could we have kept it to 30,000? 20,000?
Marcus Aurelius
How long do you want to ignore this user?
AG
Yes. I would be more comfortable with more widespread re-opening knowing there was at least one effective drug. As far as mortality effects. Unfortunately has not been proven yet. But those studies are pending. Tocilizumab will prove to reduce mortality I am certain. Hopeful HCQ / ARB trials will prove some benefits.
Pulmcrit_ag
How long do you want to ignore this user?
https://www.bloomberg.com/opinion/articles/2020-05-01/coronavirus-gilead-s-remdesivir-trial-missed-a-huge-opportunity
NawlinsAg01
How long do you want to ignore this user?
AG
Meh, pretty crappy article. Gilead has multiple ongoing trials and plans to answer the questions the author raises. The results released this week was an NIAID funded adaptive design trial, and they only released top-line results after their Data Safety Monitoring Board saw the significant reduction in time to improvement. Trust that there will be subgroup analyses, and that there will be a lot more information coming from the Gilead-sponsored trials.
Pulmcrit_ag
How long do you want to ignore this user?
Hope so, otherwise only moderately optimistic.
The New Crew
How long do you want to ignore this user?
AG
It's not like Tamaflu. "Take two pills and call me in the morning." Lol. Jack asses. It's, I will put you on this IV while monitoring you in the hospital for a few days. Here is my $40K bill.
94chem
How long do you want to ignore this user?
GIG5 said:

It's not like Tamaflu. "Take two pills and call me in the morning." Lol. Jack asses. It's, I will put you on this IV while monitoring you in the hospital for a few days. Here is my $40K bill.


As if Tamiflu does anything. Unless you're a hypochondriac, you never get to the doctor soon enough for that stuff to matter. Should be OTC if they actually want to help anybody.
Not a Bot
How long do you want to ignore this user?
AG
They have enough manufacturing capacity and raw material to have 140,000 total courses of treatment available by the end of May. Right now they have about 30,000.

They are investigating whether a shorter course of treatment could be as effective so that more people can be treated.

https://www.gilead.com/purpose/advancing-global-health/covid-19/working-to-supply-remdesivir-for-covid-19
Refresh
Page 1 of 1
 
×
subscribe Verify your student status
See Subscription Benefits
Trial only available to users who have never subscribed or participated in a previous trial.