University of Pittsburgh Medical Center (UPMC) Chief Medical Officer on COVID-19

6,376 Views | 39 Replies | Last: 5 yr ago by AggieDruggist89
Keegan99
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AG
https://inside.upmc.com/shapiro-economy-roundtable/

Quote:

As we prepared for the pandemic, we radically transformed our hospital operations to create a safe environment for patients and staff, we delayed non-urgent surgery, reducing it by 70%, and we scaled up telemedicine 38-fold, performing 250,000 visits in April.

We indeed saw a steady stream of patients but never "surged." At peak in mid-April, COVID-19 patients occupied 2% of our 5,500 hospital beds and 48 of our 750 ventilators. Subsequently, admissions have been decreasing with very few patients now coming from the community, almost all now being from nursing homes. Of note, in the 36 UPMC-owned senior facilities we have had zero positive cases.

Our outcomes are similar to the state of Pennsylvania, where the median age of death from COVID-19 is 84 years old. The few younger patients who died all had significant preexisting conditions. Very few children were infected and none died. Minorities in our communities fared equally as well as others, but we know that this is not the case nationally. In sum, this is a disease of the elderly, sick and poor.



Quote:

The question before us is what will happen as we re-open society and how should we manage it? For New York and a handful of other cities with high case rates as a result of density, travel and socioeconomic issues, they must open up in a measured step-wise manner with extensive testing, tracing and treatment.

But for the rest of the country, as people come out of their homes cautiously and safely, if we protect our vulnerable seniors, particularly those in nursing homes, we should be able keep case rates low, buying time for a potential resurgence as we bolster our supply chain and find effective intervention.

COVID-19 is a disease that ravages those with preexisting conditions whether it be immunosenescence of aging or the social determinants of health. We can manage society in the presence of this pathogen if we focus on these preexisting conditions.

What we cannot do, is extended social isolation. Humans are social beings, and we are already seeing the adverse mental health consequences of loneliness, and that is before the much greater effects of economic devastation take hold on the human condition.



Quote:

In this particular case, the problem we're not going to be able to fix in the short term is the complete eradication of the virus. The problem we can fix is to serve and protect our seniors, especially those in nursing homes. If we do that, we can reopen society, and though infectious cases may rise as in the Theodore Roosevelt, the death rate will not, providing time for the development of treatments and vaccines.



TL;DR: Open up society, but protect the elderly and vulnerable.
Satellite of Love
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Travel should be limited to and from hot spots. Turns out the NYC is the originator for much of the US.
bad_teammate said on 2/10/21:
Just imagine how 1/6 would've played out if DC hadn't had such strict gun laws.

Two people starred his post as of the time of this signature. Those 3 people are allowed to vote in the US.
tysker
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Quote:

median age of death from COVID-19 is 84 years old.
Isn't the expected median life expectancy for Americans about 80 years old?
Keegan99
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Yep. Life expectancy in the US at birth is a hair under 80.

But life expectancy at 80 is about 8 years - a little less for men, and a little more for women. In other words, about half of those that celebrate their 80th birthday will live to see 88.
DadHammer
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Great post, thank you
cone
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Quote:

We can manage society in the presence of this pathogen if we focus on these preexisting conditions.


I loathe the defeatism arrayed against this approach

"there are too many, it's impossible, only way to protect them is to lock down the full herd"
94chem
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UPMC? That's a real hospital? I thought they were just an HR-generated Bot to keep employees from missing 3 days of work.
Aggie Pharmer
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Interesting tidbit of knowledge: Pittsburgh is a sister city with Wuhan.
texan12
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Mark May+UPMC=
slacker00
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Similar findings in this report from German autopsies. They took a detailed look at 12 COVID cadavers.
Quote:

Conclusion:
The high incidence of thromboembolic events suggests an important role of COVID-19induced coagulopathy. Further studies are needed to investigate the molecular mechanism and overall clinical incidence of COVID-19related death, as well as possible therapeutic interventions to reduce it.
LINK

ETA: replied to wrong thread.
Marcus Aurelius
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I agree with this. Unusual. When it hit initially I saw a handful of 50 somethings. With a few deaths. Some otherwise healthy. Mostly travel related. Now - elderly. Institutionalized. Just as OP. Makes one think.............
KlinkerAg11
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Think what exactly? Really interested in your thoughts.
Keegan99
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Marcus Aurelius said:

I agree with this. Unusual. When it hit initially I saw a handful of 50 somethings. With a few deaths. Some otherwise healthy. Mostly travel related. Now - elderly. Institutionalized. Just as OP. Makes one think.............

That there is only a very small percentage of the non-institutionalized population that's even significantly vulnerable? Or...?
tysker
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Maybe not the forum to post this but I have a sneaking suspicion that after almost three months of fighting this, the on-the-ground medical personnel are starting to see a patient load that may run counter to some prevailing narratives and policies. I also wonder if there is a patient trend that shouldn't/can't be openly discussed in our highly politicized world.
Pasquale Liucci
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What, that the average person isn't vulnerable in a statistically significant way?
Pasquale Liucci
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KlinkerAg11 said:

Think what exactly? Really interested in your thoughts.


Same
Keegan99
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tysker said:

Maybe not the forum to post this but I have a sneaking suspicion that after almost three months of fighting this, the on-the-ground medical personnel are starting to see a patient load that may run counter to some prevailing narratives and policies. I also wonder if there is a patient trend that shouldn't/can't be openly discussed in our highly politicized world.

Some data that is significant and should be easy-to-find is really challenging to dig up. Or not exactly broadcast with enthusiasm.

For example, as mentioned by the physician above, age distributions. Or percentage of deaths from nursing homes and long-term care facilities. Hugely important factors that should be guiding public policy.


But a very, very small number of kids showing signs of disease with no tangible evidence that it's linked to COVID? That's national headlines! Spots on the nightly news!

(https://www.nbcnews.com/health/health-news/15-children-n-y-c-identified-rare-covid-linked-condition-n1200256)
cone
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Quote:

Some data that is significant and should be easy-to-find is really challenging to dig up. Or not exactly broadcast with enthusiasm.
100%

what's the plot distribution of death per state by age?

what's the % of people dying under 65 with a) BMI > 30, b) hypertension, c) diabetes d) combination of 2 or more

how is that difficult to collate?
cone
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i do think this is a disease you don't actively want to seek out

but there's a significant group of elite opinion that does not want to break the paranoia, even in the face of better news/data

the NYC serology study being my complete obsession - it wasn't dismantled like the CA serology studies, so the immediate pivot was to we can't actually protect the vulnerable

it's defeatist and we are grossly misallocating resources right now
94chem
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Quote:

I also wonder if there is a patient trend that shouldn't/can't be openly discussed in our highly politicized world.


My concern, which I probably posted 2 months ago, was what would happen when this got loose in the rural South. People talk about how wonderful the US health care system is, but in proportion to our wealth, our health care is terrible. Sure, it's great once you're sick, but the combination of individual choice and awful preventative medicine leaves many people vulnerable.

Long story short, America has this decades long reality where the poor people are the most overweight. THIS is the issue that is politically incorrect to talk about.

The OP mentions "socioeconomic issues." It alludes to "poverty." Sorry, being poor doesn't make you sick any more than it makes you a criminal. I'd like to know the average BMI of the people under 65 who are hospitalized. It's not mean-spirited. It's a legitimate question, and if we're going to write a detailed piece that confuses matters by saying "socioeconomic issues," we should stop *****-footing around what those issues are.
KlinkerAg11
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It's turned into fear porn, and it's getting old.
MiMi
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S
Quote:

what's the % of people dying under 65 with a) BMI > 30, b) hypertension, c) diabetes d) combination of 2 or more

Here is an interesting prediction of deterioration chart

Prediction for Progression Risk in Patients with COVID-19 Pneumonia: The CALL Score.
plain_o_llama
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This is the paper behind that Call Score
https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa414/5818317

It would be interesting to see if the New York data is aligned with this. Anyone know?
John Francis Donaghy
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UPMC is one of the largest and most cuttong edge hospitals in the country, and they are serving a relatively isolated mid-sized city. Not saying the message is off base overall. But their ratios of present need to present capacity is probably better than just about every other city in the US just because of UPMCs massive infrastructure in a not-so-massive city. Just thought that should be pointed out.
DTP02
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The stuff in the OP is what we need to be seeing in the media and hearing from our fed, state, and local decision-makers. It's way past time for logic and rationality to displace fear in guiding our approach to this.

Also:

Quote:

Of note, in the 36 UPMC-owned senior facilities we have had zero positive cases.


People need to be talking to UPMC about what they're doing in these facilities. How differently does this thing look if NY had been even half as effective? Roughly 25% of US fatalities have been from the .5% of the population in nursing homes. UPMC says they have protected theirs, why can't that be replicated elsewhere?

We need to be talking facts and implementing strategies which recognize those facts. Our decision-makers are weeks if not months behind on this, and we can't afford to have them continue to make wrong-headed, irrational decisions.

Some initial panic was understandable. Continuing to let irrational fear dominate discussion and policy is not.
Keegan99
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NY mandated that nursing homes admit or readmit patients without proof of being COVID negative.

In other words, NY forced potentially COVID positive patients into nursing homes.
DTP02
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Keegan99 said:

NY mandated that nursing homes admit or readmit patients without proof of being COVID negative.

In other words, NY forced potentially COVID positive patients into nursing homes.


Yeah, I know, and they also had COVID positive HCW's working in nursing homes. NY really couldn't have handled things much worse than they did, but somehow Cuomo is being treated as a heroic leader in this. It's crazy.
JP_Losman
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This type of information OP linked should be circulated through the public. People need this context to calm the ridiculous fear out there. Send it around to people you know
MAROON
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would love to read the linked report, but looks like it's not loading now.
What do you boys want for breakfast BBQ ?.....OK Chili.
Capitol Ag
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This is why I have gotten so frustrated with how the virus is being portrayed publicly and how it's become so irrational among how people are acting. No one is talking about the virus this way. As others have said, this should be focused on by the media and by our lawmakers and industry leaders. Great article by a reputable and relevant source that is very hard to argue against.

I am with others in that the goalposts has been moved and now it's about social distancing to eliminate the virus, not to flatten the curve. I was in support of the flattening but that was where I drew the line always. The fact is this is not as bad as was proposed. It's is serious. But not to a level I'm hearing now. I literally hear and see narratives switching to the "we need to stay distanced to protect our species from going extinct" and we need to "save the human race". These from mainstream science and health. This thing is no where near that threat level at all. As in billions of light years no where near. That is a straight up misrepresentation of the virus and it's potential effects on us. This IS NOT a cataclysmic eon ending event like the great dying of the Permian-Triassic extinction event or the massive extinction event that killed off the non-avian dinosaurs between the Cretaceous and Tertiary periods. Yet it's now being portrayed that way by some science mediums I follow and trust, which has been very disappointing.
ham98
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MAROON said:

would love to read the linked report, but looks like it's not loading now.
Your betters have censored it for the public good
Federale01
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In slight defense of the media, the information is not there to be released. The media has been asking for nursing home death numbers for a while. I am not defending the media much. They only care because they know the numbers are bad and will drive headlines and clicks. But they can't get the numbers.

https://www.nbcnews.com/news/amp/ncna1202281
MAROON
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some animals are more equal than others.
What do you boys want for breakfast BBQ ?.....OK Chili.
HotardAg07
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I do not find this particularly surprising or interesting. A few areas in our country have been hit hard, the rest haven't. It's widely known now that we avoided overloading our hospitals and that estimates for hospitalization were initially overestimated. If you did the same interview to a number of cities, you would get similar responses.

That should not invalidate the experience of doctors who do work in harder hit areas of New York City, Newark, New Orleans, or Detroit either. We have some Aggie doctors on this very board who have shared exactly why this virus is fearsome.

My point is not that one person's experience is more valid than the other, my point is that they're both valid and they tell the story of the virus.

I also find it so counter productive to complain about the news. We all know that the news is driven off of views and clicks and the general public viewing behavior drives the style and substance of the news they consume. Fox News isn't pushing these narratives you are saying the media is pushing, and it's largely because they're feeding the red meat that their constituency wants to see. The same reason CNN/NBC/CBS are pushing their narratives. It's well-known that people react much stronger to negative information than positive information, the Freakonomics podcast details the situation very well in their latest podcast about the challenges news organizations face in this regard.

Despite what has been said here, the age distribution of the virus has been widely known and widely distributed for literally months now. Two full months ago I posted on Facebook about the age-dependency and comorbidity dependency of CV. It wasn't some state secret being withheld from the public.


I know that it's not the intent of the messenger, but sometimes a lot of the responses to the age distribution dying has the tone of "so what, they are old and were going to die soon anyways." My grandma is in her early 80s and she has some preconditions that would make her at risk if she caught CV. I don't think that she has one foot in the grave quite yet, she still works, throws parties almost every weekend, does DIY home projects, gardening etc. If she died it would absolutely cut her life short and devastate me and my other family members robbing us of valuable time with a special person.

The fact that we went from 1 known death of CV in the US on March 1 to ~2,000 people dying every day for a fully sustained month now is a jarring and severe situation and shows the lethality and transmissability of the virus. We should start to open up and get our economy rev'd up, but we shouldn't do so in a way that disregards the very real threat of the virus and act like it's no risk to anybody under 70. This isn't a disease where you can bear all the risk of your decisions. This is a disease where your decisions risk yourself and every person you come into contact with. It should be treated that way.
JP_Losman
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the coronavirus isn't the only way to die as it turns out.
Should we make a list of ways a person can die?

How many could we come up with? thousands?
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