https://seekingalpha.com/news/3575064-sorrento-claims-covidminus-19-cure

Unclear to me from that short article, and this is obviously very early on this unsubstantiated claim, but can the antibody be synthesized or do we have to rely on extraction from recovered patients?

How long to get FDA approval if true?

I am not an expert, but I thought I had read that labs are working on developing synthetic antibodies from those seen in recovered patients

Was curious as well. The stock market as a whole hasn't responded, so must be a whole lot more to the story.

Kool said:

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Odd story with very little info. I am NOT a virologist or ID, but the only way I could see this working would be to give it IV, or with a large IM dosage, post exposure or immediately pre exposure, akin to convalescent plasma. How else would a blocking antibody remain in circulation long enough to confer immunity?

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This appears to be more or less factory made convalescent plasma? (Not a doctor)

Windy City Ag said:

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I could see the SEC investigating this. . . . . There was a block trade right at the open of nearly a million shares, which is nearly 1% of the firm's overall float. That is old school pump and dump right there and not a very clever one.

Alternatively, it could be one of the many headline scanning algo trading robots seeing the spike in news volume in a very popular area of the stock market and doing its duty.

Or maybe someone is just a believer and betting big.

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CYDY is the same story.

That article is trash. As noted above EVERYONE is working on therapeutic antibodies. I assure you that all the companies in this game have equally impressive in vitro and mouse data.

Doesn't mean anything until it's in people. Which will be many months from now because bio manufacturing is slow.

https://www.scmp.com/news/hong-kong/health-environment/article/3084440/coronavirus-call-hong-kong-covid-19-survivors

The whole plasma thing seeems a great kill shot, if someone can manufacture this outside the body it would represent more or less a treatment.

A little more info.....

https://www.foxnews.com/science/covid-cure-california-biopharmaceutical-coronavirus-antibody-breakthrough

Few issues:

First, no mention of human clinical trials. Until we show that it works in people it's just a pipedream.

Second, to my knowledge all antibody therapies are injections. I think the half life of most are a few weeks, so you could really only expect a month or two of immunity at best from each injection. Great for treatment, not great for prevention.

Third, antibody therapies are horrendously expensive. Like tens of thousands per injection. Treating/prophylaxing all non-immune people in just the US with a synthetic antibody would cost more money than exists in the world.

gotsand said:

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SkiMo said:

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Beaux12 said:

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A little more info.....

https://www.foxnews.com/science/covid-cure-california-biopharmaceutical-coronavirus-antibody-breakthrough

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Quote:

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"As soon as it is infused, that patient is now immune to the disease," Dr. Brunswick said to Fox News. "For the length of time, the antibody is in that system. So, if we were approved [by the FDA] today, everyone who gets that antibody can go back to work and have no fear of catching COVID-19."

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This seems like a rather bold statement. I mean, you don't just say **** like this unless you're 100% confident, right?

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He's only 100% confident that his friends and family just got insanely wealthy.

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their stock was up $250% earlier today.

AggieOO said:

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gotsand said:

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SkiMo said:

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Beaux12 said:

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A little more info.....

https://www.foxnews.com/science/covid-cure-california-biopharmaceutical-coronavirus-antibody-breakthrough

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Quote:

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"As soon as it is infused, that patient is now immune to the disease," Dr. Brunswick said to Fox News. "For the length of time, the antibody is in that system. So, if we were approved [by the FDA] today, everyone who gets that antibody can go back to work and have no fear of catching COVID-19."

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This seems like a rather bold statement. I mean, you don't just say **** like this unless you're 100% confident, right?

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He's only 100% confident that his friends and family just got insanely wealthy.

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their stock was up $250% earlier today.

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Honest question because I'm not smart.... is this not teetering on the lines of illegal? Fraudulent claims? Market manipulation?

SkiMo said:

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AggieOO said:

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gotsand said:

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SkiMo said:

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Beaux12 said:

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A little more info.....

https://www.foxnews.com/science/covid-cure-california-biopharmaceutical-coronavirus-antibody-breakthrough

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Quote:

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"As soon as it is infused, that patient is now immune to the disease," Dr. Brunswick said to Fox News. "For the length of time, the antibody is in that system. So, if we were approved [by the FDA] today, everyone who gets that antibody can go back to work and have no fear of catching COVID-19."

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This seems like a rather bold statement. I mean, you don't just say **** like this unless you're 100% confident, right?

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He's only 100% confident that his friends and family just got insanely wealthy.

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their stock was up $250% earlier today.

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Honest question because I'm not smart.... is this not teetering on the lines of illegal? Fraudulent claims? Market manipulation?

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Teetering? No. Trading off non-public information is illegal as is deceptively manipulating stock prices. Not always easy to prove and the SEC has turned a blind eye more than once (looking at you Elon).

Heck, it's even popular with sitting U.S. Congresspersons.

ramblin_ag02 said:

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Few issues:

First, no mention of human clinical trials. Until we show that it works in people it's just a pipedream.

Second, to my knowledge all antibody therapies are injections. I think the half life of most are a few weeks, so you could really only expect a month or two of immunity at best from each injection. Great for treatment, not great for prevention.

Third, antibody therapies are horrendously expensive. Like tens of thousands per injection. Treating/prophylaxing all non-immune people in just the US with a synthetic antibody would cost more money than exists in the world.

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I've done antibody drug development before, and worked on some infectious disease projects. The financial model was always a bit murky. The idea for the staph one was that it would be for sepsis patients. At that stage a $50,000 intervention doesn't seem so outlandish.

I assume the model here is that the government will buy up whatever supply you can make, no questions asked. Also, even if the company that comes out with an effective antibody treatment loses 2 billion dollars on it, the publicity for saving the world will be worth a lot more.

Because of development timelines though it's hard for me to see how an antibody therapy could get to market much faster than a vaccine. From the development and manufacturing perspective they are quite similar. The antibody clinical trial would be faster though.

Thank you to this thread for a quick 60% in the market today.

Look at these responses.
staggering to me how cynical everyone is these days- rightly or wrongly

SkiMo said:

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Beaux12 said:

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A little more info.....

https://www.foxnews.com/science/covid-cure-california-biopharmaceutical-coronavirus-antibody-breakthrough

---

Quote:

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"As soon as it is infused, that patient is now immune to the disease," Dr. Brunswick said to Fox News. "For the length of time, the antibody is in that system. So, if we were approved [by the FDA] today, everyone who gets that antibody can go back to work and have no fear of catching COVID-19."

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This seems like a rather bold statement. I mean, you don't just say **** like this unless you're 100% confident, right?

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Well, if you're Theranos, you just get one rich, old, white, senile has-been to agree with you, and it's okay.

I am more interested in as a four day cure if you get it. If that is true it is beter than tamiflu and those of us high risk would not be afraid to go back fully into the world.

SkiMo said:

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AggieOO said:

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gotsand said:

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SkiMo said:

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Beaux12 said:

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A little more info.....

https://www.foxnews.com/science/covid-cure-california-biopharmaceutical-coronavirus-antibody-breakthrough

---

Quote:

---

"As soon as it is infused, that patient is now immune to the disease," Dr. Brunswick said to Fox News. "For the length of time, the antibody is in that system. So, if we were approved [by the FDA] today, everyone who gets that antibody can go back to work and have no fear of catching COVID-19."

---

This seems like a rather bold statement. I mean, you don't just say **** like this unless you're 100% confident, right?

---

He's only 100% confident that his friends and family just got insanely wealthy.

---

their stock was up $250% earlier today.

---

Honest question because I'm not smart.... is this not teetering on the lines of illegal? Fraudulent claims? Market manipulation?

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Rich people never go to jail.