COVID mortality among hospitalized patients in the UK drops from 6+% to ~1%

2,950 Views | 13 Replies | Last: 5 yr ago by Picadillo
Keegan99
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AG


https://www.cebm.net/covid-19/declining-death-rate-from-covid-19-in-hospitals-in-england/

Quote:

The reasons for this steep and continual decline in the deaths per day in the hospital of patients with COVID-19 are unknown and should be explored. Potential reasons could include:

Older patients who had recovered from COVID-19 but could not be discharged to care homes have places that have over recent weeks become available. This would not, however, explain the decline that started from 9 April 2020.

Patients with COVID-19 in late March and early April included a significant proportion of patients who caught the infection in hospital. These patients, because they were in hospital, were more likely to be sicker and more vulnerable than patients who acquired infection in the community and so more likely to die from COVID-19. As patients with community-acquired infections became a greater proportion of patients in hospital the hospital death rate fell. However, this would not explain why the death rate has fallen continually for approximately 8 weeks with no signs that the decline has yet plateaued.

Clinicians have become more skilled and adept at treating patients with COVID-19.
Patients overtime being admitted are becoming younger with fewer comorbidities, although there is no evidence of this in the daily hospital death data which, if anything, suggests a greater proportion of deaths in hospital are over the age of 60 than at the peak of deaths in early April.

Patients are entering the hospital with less severe disease, which could be a reflection of either the disease becoming less severe or hospitals that are now less concerned with being unable to manage peak infections being more willing to admit patients with lower disease severity than they would admit in early April.

The reasons for the declining death rate in hospitals may be a combination of one or all of these factors or due to some other reason, we have not considered. In either case, further research is warranted to understand why the hospital death rate has declined so markedly over the past 8 weeks.



This is why you should be skeptical of forecast fatalities based on hospitalization metrics. The "conversion rate" from hospitalization to death is likely not even close to a constant, especially if that constant is estimated using months-old data.

Incidentally this also would indicate a current IFR well below 0.5%. More likely it would be closer to 0.2%, if that.
corleoneAg99
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"Clinicians have become more skilled and adept at treating patients with COVID-19.

Patients overtime being admitted are becoming younger with fewer comorbidities,"

jamey
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Seems obvious to me.


In march when they only tested the very sick there was a higher death rate among positives. The positive cases also trended older back then, when only the very sick were tested



If a disease selectively kills the older then testing only the very sick selects the older too
Forum Troll
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Great news. Their per capita death rate is worst in the world for any major nation.
GAC06
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jamey said:

Seems obvious to me.


In march when they only tested the very sick there was a higher death rate among positives. The positive cases also trended older back then, when only the very sick were tested



If a disease selectively kills the older then testing only the very sick selects the older too


This is saying the death rate among hospitalized patients is lower. Presumably hospitalized patients were always getting tested.
Keegan99
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Depends on how you define "major". Belgium is reportedly significantly worse.

("Reportedly" because such rankings assume something close to uniform international reporting standards on such figures, which is not at all the case. Sweden, for example, tallies any death among any person with a COVID+ test in the last 30 days, regardless of cause, as a COVID fatality. Other countries often require much more strict criteria. Hence apples to oranges comparisons.)
jamey
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GAC06 said:

jamey said:

Seems obvious to me.


In march when they only tested the very sick there was a higher death rate among positives. The positive cases also trended older back then, when only the very sick were tested



If a disease selectively kills the older then testing only the very sick selects the older too


This is saying the death rate among hospitalized patients is lower. Presumably hospitalized patients were always getting tested.



In that case I would also guess the older and higher risk are more careful now whereas we've all seen the videos of bars, beaches, protests...etc packed with young people.

So the prevellance of exposure is also tilted heavily towards the young, and though some may require hospitalization, it's a shorter duration and lower death rate
Forum Troll
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Keegan99 said:

Depends on how you define "major". Belgium is reportedly significantly worse.

("Reportedly" because such rankings assume something close to uniform international reporting standards on such figures, which is not at all the case. Sweden, for example, tallies any death among any person with a COVID+ test in the last 30 days, regardless of cause, as a COVID fatality. Other countries often require much more strict criteria. Hence apples to oranges comparisons.)


You are right. 2nd worst to Belgium. Not counting Andorra and San Marino.
GAC06
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It says that in the article, and in the snippet in the OP
AgsMyDude
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Follows along with this Dr's experience at UPMC

https://www.pennlive.com/news/2020/06/upmc-doctor-sees-too-much-focus-on-rising-covid-19-cases-too-little-on-declining-severity-and-hospitalizations.html

Quote:

"In summary, what our experience shows is that fewer people are being admitted, and when they are, they tend to be much less sick than at the beginning or at the peak phases of the pandemic," he said.

Yealy said the declines might result from factors such as doing a good job of protecting the elderly and others who are highly vulnerable, and a rising portion of new cases involving younger people who are healthier and less likely to need hospitalization.

He also said UMPC has improved tools for helping the sickest patients, including the drug Remdesivir, and has "gained experience in how to best care for" COVID-19 patients. He noted that early in the pandemic, doctors usually put the sickest patients on breathing ventilators. But UPMC learned "it was difficult for them to successfully come off, and their outcomes simply aren't as good."



I think Marcus has shared a similar sentiment in his posts.
Pasquale Liucci
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Yep, he definitely said that he has people walking out today who unquestionably would have died two months ago.
Austin Ag
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Too early for these facts. It's not November yet.
Barnyard96
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Thank you sir. Please keep us posted. I know big decisions are pending in July and this is encouraging.
Gordo14
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Just a reminder that it's also a function of how many patients they are treating at a given time. I bet if you plotted total hospitalized it would follow a similar - maybe steeper- trend.
Picadillo
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Meantime in the US...


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