Published last week, post peer-review.
This was an observational study examining 1200+ cases in Massachusetts. People with A+ were no more likely to have severe symptoms than the other types.
https://link.springer.com/article/10.1007/s00277-020-04169-1#Sec2
This was an observational study examining 1200+ cases in Massachusetts. People with A+ were no more likely to have severe symptoms than the other types.
https://link.springer.com/article/10.1007/s00277-020-04169-1#Sec2
Quote:
Of the 1289 patients who tested positive, 440 (34.2%) were blood type A, 201 (15.6%) were blood type B, 61 (4.7%) were blood type AB, and 587 (45.5%) were blood type O. On univariate analysis, there was no association between blood type and any of the peak inflammatory markers (peak WBC, p = 0.25; peak LDH, p = 0.40; peak ESR, p = 0.16; peak CRP, p = 0.14) nor between blood type and any of the clinical outcomes of severity (admission p = 0.20, ICU admission p = 0.94, intubation p = 0.93, proning while intubated p = 0.58, ECMO p = 0.09, and death p = 0.49). After multivariable analysis, blood type was not independently associated with risk of intubation or death (referent blood type A; blood type B: AOR: 0.72, 95% CI: 0.421.26, blood type AB: AOR: 0.78, CI: 0.331.87, blood type O: AOR: 0.77, CI: 0.511.16), rhesus factor positive (Rh+): AOR: 1.03, CI: 0.931.86. Blood type A had no correlation with positive testing (AOR: 1.00, CI: 0.881.13), blood type B was associated with higher odds of testing positive for disease (AOR: 1.28, CI: 1.081.52), AB was also associated with higher odds of testing positive (AOR: 1.37, CI: 1.021.83), and O was associated with a lower risk of testing positive (AOR: 0.84, CI: 0.750.95). Rh+ status was associated with higher odds of testing positive (AOR: 1.23, CI: 1.0031.50). Blood type was not associated with risk of intubation or death in patients with COVID-19.