South African Strain worst yet - medical Pros ink

3,884 Views | 21 Replies | Last: 5 yr ago by Ags4DaWin
Born&Raised
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
6:57p, 1/25/21
(I know it's NPR - but get over it - the rest of the link were paid/blocked)

- basically what it says is that it the current Moderna Vaccine produces 6 times LESS anti-bodies against the South African Strain.

That sounds like a lot but then they say it is not that big a deal - it still works but will not put a number on it. Like does it move from 95% to 60% or 85%

Anyone got any info? Medical pros?

https://www.npr.org/sections/coronavirus-live-updates/2021/01/25/960341384/moderna-finds-covid-19-vaccine-less-effective-against-variant-found-in-south-afr
Reply Quote
1
1 edit
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to Born&Raised • 7:12p, 1/25/21
AG
you won't get a comp to the stated 95% without a similar clinical trial
Reply Quote
3
Born&Raised
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to cone • 7:32p, 1/25/21
cone said:
you won't get a comp to the stated 95% without a similar clinical trial


What does that mean... a comp... is that not what they found - 6 x less antibodies but the overall rate of effectiveness is still "effective"

What the heck does that mean?
Reply Quote
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to Born&Raised • 7:45p, 1/25/21
AG
comp is short for comparison

turn it back on you - how did they get the 95% number

wouldn't they have to do a similar test to get a similar number?
Reply Quote
1 edit
Born&Raised
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to cone • 7:47p, 1/25/21
cone said:
comp is short for comparison

turn it back on you - how did they get the 95% number

wouldn't they have to do a similar test to get a similar number?


I know what comp means, boss - I mean why do they need a comp if they are already have an idea that it is 6 times less antibodies.

Shouldn't they have an effectiveness number?
Or at least an idea...
Reply Quote
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to Born&Raised • 7:51p, 1/25/21
AG
I think that's why they ran phase 3 clinical trials. to determine effectiveness.

But I'll let the real scientists give you a better answer to your question
Reply Quote
Born&Raised
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
12:04p, 1/28/21
And bump....

https://www.kbtx.com/2021/01/28/virus-variant-from-south-africa-detected-in-us-for-1st-time/?fbclid=IwAR2Yogem5-C7HPmCyC_F-a1-j4wmupqqgp0vA1PEfKN8o1xa5Jjflwo8OcI
Reply Quote
Dad
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
4:30p, 1/28/21
AG
Just wait until the South African variant combines with Ebola.... Ebovid 21. It is game over after that.
Reply Quote
26
Charpie
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to Dad • 4:55p, 1/28/21
AG
Dad said:
Just wait until the South African variant combines with Ebola.... Ebovid 21. It is game over after that.
This made me giggle irl
Reply Quote
2
GAC06
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
5:00p, 1/28/21
AG
EbovAIDS-21

Everyone get a copy of The Road for instructional purposes
Reply Quote
5
Captain Pablo
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to Born&Raised • 1:34p, 1/29/21
AG
Born&Raised said:
(I know it's NPR - but get over it - the rest of the link were paid/blocked)

- basically what it says is that it the current Moderna Vaccine produces 6 times LESS anti-bodies against the South African Strain.

That sounds like a lot but then they say it is not that big a deal - it still works but will not put a number on it. Like does it move from 95% to 60% or 85%

Anyone got any info? Medical pros?

https://www.npr.org/sections/coronavirus-live-updates/2021/01/25/960341384/moderna-finds-covid-19-vaccine-less-effective-against-variant-found-in-south-afr


Wouldn't it be "fewer"?

Or in this particular instance, "FEWER"?
Reply Quote
3
CowtownEng
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
1:40p, 1/29/21
The media is having a field day with the continuous stream of fear porn. Stop being such a wet blanket.
Reply Quote
25
VanZandt92
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
1:58p, 1/29/21
I think the original post title probably shouldn't use the word "worst" as it is too subjective. That being said, I can tell you I am worried about this strain , B1.351, that is being called the South Africa strain. The one called UK isB.1.1.7. These strains seem to demonstrate that they are achieving dominance by outcompeting other strains quickly. Their mutations don't appear to be carried on by chance and indicate increased transmission . Multiple colleagues are also worried. Hopefully the anxiety is unfounded.
Reply Quote
2 edits
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to VanZandt92 • 2:45p, 1/29/21
AG
Increased transfusion?

Mutations not by chance?

can you explain?
Reply Quote
Bucketrunner
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
3:02p, 1/29/21
Biological warfare???? Again?
Reply Quote
1
VanZandt92
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to cone • 3:13p, 1/29/21
cone said:
Increased transfusion?

Mutations not by chance?

can you explain?


Transmission edit. I'm typing on my iPhone.
Reply Quote
1 edit
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to VanZandt92 • 3:22p, 1/29/21
AG
oh okay for sure

what about the mutations not being by chance?
Reply Quote
4
VanZandt92
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to cone • 4:00p, 1/29/21
cone said:
oh okay for sure

what about the mutations not being by chance?


Some mutations are propagated by chance but some increase fitness of the virus. The two mentioned strains likely have increased fitness.
Reply Quote
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to VanZandt92 • 5:43p, 1/29/21
AG
but those happened by chance

due to the numbers of cumulative infections and transmissions
Reply Quote
2
VanZandt92
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to cone • 7:00p, 1/29/21
cone said:
but those happened by chance

due to the numbers of cumulative infections and transmissions


Propagated by chance versus being more competitive in either survival or transmission. The initial mutations are all by chance. You aren't getting this are you? What needs to be explained?
Reply Quote
cone
User Profile
Private Message
Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to VanZandt92 • 7:14p, 1/29/21
AG
I guess I'm just trying to get you to be more clear

I think what you're saying is that mitigation and treatment efforts are leading to vacc escape and more infectious strains

totally agree there

I'm just hoping I spelled out what you meant
Reply Quote
The_Fox
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to Dad • 11:02p, 1/30/21
Dad said:
Just wait until the South African variant combines with Ebola.... Ebovid 21. It is game over after that.
I still would not wear a mask even for Ebovid 21.
Reply Quote
2
Ags4DaWin
User Profile Ignore User Stop Ignoring
How long do you want to ignore this user?
24 hours One week Permanently Cancel
In reply to VanZandt92 • 12:30a, 1/31/21
VanZandt92 said:
cone said:
oh okay for sure

what about the mutations not being by chance?


Some mutations are propagated by chance but some increase fitness of the virus. The two mentioned strains likely have increased fitness.


Lockdowns are making the virus more lethal and more fit in that they last longer in the environment and are more transmissable.

the lockdowns need to stop now otherwise we will continue to see more strains like this crop up.

in order to transmit during a lockdown the virus must have better environmental survival and must be more infective requiring a lower viral load for infection.

this skews virus survival in the population to the more virulent, more transmissable, and the environmentally stable mutations.

until the lockdowns stop you will see the virus skew more and more this direction.
Reply Quote
4
2 edits
Refresh
Page 1 of 1
 
×
subscribe Verify your student status
See Subscription Benefits
Trial only available to users who have never subscribed or participated in a previous trial.