Post here if you've had COVID-19 twice

4,142 Views | 16 Replies | Last: 4 yr ago by Rubble
Old Town Ag
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AG
or directly know someone who has.
aggiederelict
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My wife's niece had it twice in NYC. 11 years old. Not very common would be my guess but they were spaced out 8 months apart and her mother works in the ER so get exposed quite a bit.
Old Buffalo
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AG
What's the purpose of this?

There's like 50 documented cases out of 26.7m. 0.0001875%.

https://bnonews.com/index.php/reinfection-tracker-suspected-cases/
“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.”
GAC06
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AG
But dozens on TexAgs
Petrino1
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I think the majority of people who claim to have gotten it twice, really just have long-term lingering symptoms. The long haulers. 10% of people infected with covid experience lingering symptoms up to 6-9 months.

Ive had lingering Covid symptoms for 8 months now. Initially when my symptoms came back the second time I thought I got reinfected, but now I just realize Im one of the "long haulers."
The Big12Ag
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It doesn't seem to have value as something to be fearful of but it does seem to have value if it encourages people to get vaccinated, having now recognized being sick previously doesn't guarantee anything.

Still, the documented numbers are too tiny to drive decisions like at this point.
evestor1
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Mother-in-law in New Braunfels tested positive for antibodies last april-may timeframe after a bad battle with it two months prior. Then she tested positive again around jan 1 2021.

so it is possible.
Tom Doniphon
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I've had it twice... last August and again in January. Confirmed with blood antibody tests.

Probably because I live life without a mask or any fear of that crap. Oh well... I'm a survivor!
Dad
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AG
I know someone that thought she had it at least three times. It turned out that she is just crazy but one of the times she did get a positive test so she might have had it once but in all she tested more than 10 times so maybe it was a false positive.
HotardAg07
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AG
Relevant


Quote:

INTRODUCTION
Immunological memory is the basis for durable protective immunity after infections or vaccinations. Duration of immunological memory after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19 is unclear. Immunological memory can consist of memory B cells, antibodies, memory CD4+ T cells, and/or memory CD8+ T cells. Knowledge of the kinetics and interrelationships among those four types of memory in humans is limited. Understanding immune memory to SARS-CoV-2 has implications for understanding protective immunity against COVID-19 and assessing the likely future course of the COVID-19 pandemic.

RATIONALE
Assessing virus-specific immune memory over at least a 6-month period is likely necessary to ascertain the durability of immune memory to SARS-CoV-2. Given the evidence that antibodies, CD4+ T cells, and CD8+ T cells can all participate in protective immunity to SARS-CoV-2, we measured antigen-specific antibodies, memory B cells, CD4+ T cells, and CD8+ T cells in the blood from subjects who recovered from COVID-19, up to 8 months after infection.

RESULTS
The study involved 254 samples from 188 COVID-19 cases, including 43 samples at 6 to 8 months after infection. Fifty-one subjects in the study provided longitudinal blood samples, allowing for both cross-sectional and longitudinal analyses of SARS-CoV-2specific immune memory. Antibodies against SARS-CoV-2 spike and receptor binding domain (RBD) declined moderately over 8 months, comparable to several other reports. Memory B cells against SARS-CoV-2 spike actually increased between 1 month and 8 months after infection. Memory CD8+T cells and memory CD4+ T cells declined with an initial half-life of 3 to 5 months. This is the largest antigen-specific study to date of the four major types of immune memory for any viral infection.

Among the antibody responses, spike immunoglobulin G (IgG), RBD IgG, and neutralizing antibody titers exhibited similar kinetics. Spike IgA was still present in the large majority of subjects at 6 to 8 months after infection. Among the memory B cell responses, IgG was the dominant isotype, with a minor population of IgA memory B cells. IgM memory B cells appeared to be short-lived. CD8+ T cell and CD4+ T cell memory was measured for all SARS-CoV-2 proteins. Although ~70% of individuals possessed detectable CD8+ T cell memory at 1 month after infection, that proportion declined to ~50% by 6 to 8 months after infection. For CD4+ T cell memory, 93% of subjects had detectable SARS-CoV-2 memory at 1 month after infection, and the proportion of subjects positive for CD4+ T cells (92%) remained high at 6 to 8 months after infection. SARS-CoV-2 spike-specific memory CD4+ T cells with the specialized capacity to help B cells [T follicular helper (TFH) cells] were also maintained.
The different types of immune memory each had distinct kinetics, resulting in complex interrelationships between the abundance of T cell, B cell, and antibody immune memory over time. Additionally, substantially heterogeneity in memory to SARS-CoV-2 was observed.

CONCLUSION
Substantial immune memory is generated after COVID-19, involving all four major types of immune memory. About 95% of subjects retained immune memory at ~6 months after infection. Circulating antibody titers were not predictive of T cell memory. Thus, simple serological tests for SARS-CoV-2 antibodies do not reflect the richness and durability of immune memory to SARS-CoV-2. This work expands our understanding of immune memory in humans. These results have implications for protective immunity against SARS-CoV-2 and recurrent COVID-19.

Goodbull_19
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AG
I have a close friend who just got covid for the second time. First infection 8 months ago, very mild symptoms. Totally asymptomatic this time, was only tested due to an exposure.

Make of it what you will.
smjack1
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My daughter-in-law had it twice. Once in April and again in November. But in between she had some very aggressive chemo treatments, so I think that might have destroyed any immunity she had from the first infection.
ORAggieFan
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This is one of the many problems with a PCR test. A positive PCR test does not mean you've had Covid.
CapAmr05
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AG
I had it the first time in March of 2020: dry cough, spiking fevers, chills/sweats, nausea, weakness, fatigue, vertigo

Just recently got it again this last week: dry cough, spiking fever, chills sweats

This second go round has been much 'easier', the symptoms are less intense and it feels like I'm recovering from them quicker.
JB!98
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AG
I a co-worker that had it in August of last year and was sick for a month. Got again two weeks ago and was sick for a week. I had a hard time believing it, but it looks like she did catch it twice.
Today, unfortunately, many Americans have good reason to fear that they will be victimized if they are unable to protect themselves. And today, no less than in 1791, the Second Amendment guarantees their right to do so. - Justice Samuel Alito 2022
White Liberals=The Worst
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GAC06 said:

But dozens on TexAgs
"I swear I had something back in January or Feb...just felt funky and achy for a few days out of nowhere...therefore I know I had Covid."

Couldn't tell you how many times I have heard people say this.
94chem
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I had two A's in the Pepsi CHALLENGE back in about '82
94chem,
That, sir, was the greatest post in the history of TexAgs. I salute you. -- Dough
Rubble
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AG
Can I make a thread that says post here if you haven't gotten it once?
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