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GLP-1 Peptides Mounjaro/Tirzepatide, Ozempic/Wegovy/Semaglutide - any experience?

22,459 Views | 80 Replies | Last: 28 days ago by AggieRuss
Teddy Perkins
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AG
The new South Park special "The End of Obesity" has the kids navigating the American health care system to get Cartman semaglutide meds. Spot on.
wangus12
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AG
Just reiterating. Please make sure you are maintaining a consistent workout program while taking these meds. These things take a decent chunk of lean body mass for the weight loss as well so you want to be training to help maintain your strength.
True Anomaly
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AG
wangus12 said:

Just reiterating. Please make sure you are maintaining a consistent workout program while taking these meds. These things take a decent chunk of lean body mass for the weight loss as well so you want to be training to help maintain your strength.
100%

You should also do consistent resistance training when dieting even if you're not using a GLP1.

Preferably, your resistance training should have more of a hypertrophy focus in order to preserve muscle
Teddy Perkins
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AG
True Anomaly said:

wangus12 said:

Just reiterating. Please make sure you are maintaining a consistent workout program while taking these meds. These things take a decent chunk of lean body mass for the weight loss as well so you want to be training to help maintain your strength.
100%

You should also do consistent resistance training when dieting even if you're not using a GLP1.

Preferably, your resistance training should have more of a hypertrophy focus in order to preserve muscle


How much daily protein should we target? 1g per lb is what I've seen but there's no way I'm hitting that target. I assume it's lower if you have a BMI over 30. More of 1g per lb lean body mass might make more sense?
True Anomaly
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AG
Teddy Perkins said:

True Anomaly said:

wangus12 said:

Just reiterating. Please make sure you are maintaining a consistent workout program while taking these meds. These things take a decent chunk of lean body mass for the weight loss as well so you want to be training to help maintain your strength.
100%

You should also do consistent resistance training when dieting even if you're not using a GLP1.

Preferably, your resistance training should have more of a hypertrophy focus in order to preserve muscle


How much daily protein should we target? 1g per lb is what I've seen but there's no way I'm hitting that target. I assume it's lower if you have a BMI over 30. More of 1g per lb lean body mass might make more sense?
Anywhere from 0.7-1.2 g/pound of lean body weight is the optimal goal for body recomposition, based on the consensus of evidence

In my view, it's based upon your body fat percentage. The higher your body fat percentage is, then the harder it is to calculate your protein goals- so you just need to make an adjustment
- If you're actually 15% BF or less, then you can just use your actual body weight for the protein goal
- If you're 20% BF or above, then using "ideal body weight" for your protein goal is probably better just because it's easier to fit in and still see results

I truly believe ALL adults would benefit from consistently eating > 100 grams/protein per day

But none of this is truly optimized unless you do consistent resistance training, biased towards hypertrophy
KidDoc
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AG
I agree with the resistance stuff. I've been off GLP1 since my insurance stopped covering it nearly 2 years ago. Drifted up some but stablized and now dropping a bit with the only change is adding Tonal in 11/2023. Game changing machine for me, first time I've enjoyed lifting since high school and I'm actually seeing strength gains!

No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
TequilaMockingbird
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Went to the doc today. A1C is down 2 points and I've lost about 12 pounds.
AggieMainland
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Starting Zepbound next week. Interested to see how it goes.
KidDoc
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AG
AggieMainland said:

Starting Zepbound next week. Interested to see how it goes.
Eat 1/2 portions, high protein, high fiber, take a multivitamin. Slow down your eating pace significantly or you will overeat and feel horribly bloated.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Tailgate88
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AG
I started a thread for this video but thought this part would be relevant to this thread. Video is queued up at the part discussing Ozempic. Fair warning they are not fans.

AggieRuss
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AG
I have crossfit trained for 1 year and have eaten healthy prepped meals consistently for the last year. I'm 5'10", 47 years old and started at 215 pounds. I was definitely stronger from working out but could only lose about 7 pounds, had flab everywhere, had crazy sugar urges and always thought about food. I had a BMI of 33%. I have been on a compounded semaglutide for about 4 months. I still workout 4-5 days/week. I still eat prepped meals but I now weigh 179 pounds. My BMI is about 23%. The semaglutide is the only thing I have changed. I went to my yearly checkup 2 weeks and all of my blood tests came back perfect! No pre-diabetes or anything even close to address. My doc emailed me to say that I was in exceptional shape and to keep up the semaglutide, eating properly and working out. My goal is 170-175. Eat properly, take fiber and drink a ton of water.
 
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