Lots of great information on these forums....I'm sure the answer is here somewhere, but it's like trying to find a needle in a stack of needles.
Are there any proven therapies yet?
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Last: 5 yr ago by JokkerZ
Agree we need a FAQ page....lots of data hard to sift
There is an antiviral that has been shown to lessen the severity.
There is a steroid that has been shown to reduce deaths in severe cases.
There are some IL-6 antibodies that seem to help with the cytokine storm.
"Proven" is a really big word. All the stuff that seems to be working is still part of ongoing clinical trials.
There is a steroid that has been shown to reduce deaths in severe cases.
There are some IL-6 antibodies that seem to help with the cytokine storm.
"Proven" is a really big word. All the stuff that seems to be working is still part of ongoing clinical trials.
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
This is great info. Really appreciate the medical community for what they have done.Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Are you not sold on dexamethasone? That UK study made it look good
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
I just read the summary. Full paper not published yet I think. Promising.
Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Thank you for this info, and all the rest of the info you've shared through this. You docs giving the straight information on whats really going on with the virus on this forum are a breath of fresh air in a world gone mad. I greatly appreciate it, and I suspect a lot of others do too.
That's where the steroids come in. The study suggests dexamethazone is the best choice but who knows.Quote:
Are you not sold on dexamethasone? That UK study made it look good
Are all of these treatment only for hospitalized patients? Are there any outpatient treatments that have proven effective?
Out of curiosity, are the people that would've died earlier in the spring (but aren't now, thanks to new knowledge of treatments) generally taking a while to be discharged? Or are they recovering fairly quickly?Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Yes. 100%.
Is this all common knowledge now? What if you have COVID and head to the hospital and the docs are pushing some treatment other than this? Would you recommend a patient telling the staff "This is what I want, Remdesivir, Tocilizumab..."Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Would you recommend shopping hospitals for a treatment regimen?
I don't have it, just curious.
Formerly Willy Wonka
His anecdotal evidence is promising, but that sounds eerily familiar to anecdotes and HCQ+Zinc early on which wasn't proven to be effective.
yeah sureBowSowy said:
His anecdotal evidence is promising, but that sounds eerily familiar to anecdotes and HCQ+Zinc early on which wasn't proven to be effective.
It should be. Stay away from hospitals that aren't using these regimens.Willy Wonka said:Is this all common knowledge now? What if you have COVID and head to the hospital and the docs are pushing some treatment other than this? Would you recommend a patient telling the staff "This is what I want, Remdesivir, Tocilizumab..."Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Would you recommend shopping hospitals for a treatment regimen?
I don't have it, just curious.
I don't know that I would go that far. Outside of remdesivir, no other treatment listed has high quality published data that demonstrates efficacy, and even remdesivir's data is not exactly impressive. My hospital currently uses all of the above, but myself as well as my critical care docs are very upfront about the fact that we have no clue whether any of these therapies are truly effective.Marcus Aurelius said:It should be. Stay away from hospitals that aren't using these regimens.Willy Wonka said:Is this all common knowledge now? What if you have COVID and head to the hospital and the docs are pushing some treatment other than this? Would you recommend a patient telling the staff "This is what I want, Remdesivir, Tocilizumab..."Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Would you recommend shopping hospitals for a treatment regimen?
I don't have it, just curious.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Thanks everyone, especially Marcus. Great discussion and very helpful.
Respectfully disagree. Already 2 papers published for remdesivir and toci. Anecdotal I get it but seeing it firsthand. This regimen is working. Call me out later if the Timi level trials says otherwise.
No need to call anyone out, and no one is asking for TIMI level evidence. We have had numerous RCTs already published for various therapies which have guided us to our current regimens. We use the same regimen at our hospital currently, but they are mostly unproven therapies and it is important that the general public and our patients know that they are unproven. I would also not fault anyone that decided not to use them without more evidence outside of dexamethasone and remdesivir potentially.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Thanks Doc
Anyone else screenshot this so they can give to their doc if anyone we know ends up in the ER? I know I did. And I'm kicking and screaming if they try to put me on a vent.
How do you know what a hospital's treatment plan is? Would have a choice of several in the metroplex if I got sick but not sure how to determine which would be best. Hope it won't matter!
Marcus Aurelius said:
Absolutely. Remdesivir at admission. Tocilizumab at cytokine storm. Full anticoagulation. Convalescent plasma. Plus minus steroids. Avoid intubating. People arent dying at my hospital like they were in beginning.
Anything proven yet prior to hospital admission? HCQ still the leader there?
No. Unfortunately. HCQ not holding up well in studies. Vaccination will be the key.
HCQ In combo with zinc seems to work if you're mildly symptomatic by preventing you from becoming acutely ill. But if the cytokines storm has already started it doesn't seem to help Much.
In 2-3 weeks a monoclonal antibody RCT study using Leronlimab
Will be unblinded. This drug might have promise.
Will be unblinded. This drug might have promise.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Great news. Another drug effecting different mechanism of action.
ocag said:
How do you know what a hospital's treatment plan is? Would have a choice of several in the metroplex if I got sick but not sure how to determine which would be best. Hope it won't matter!
The best scenario is to end up at one of the teaching/research hospitals. They will have more access to the meds you see docs on here mentioning.
How does one find out the teaching/research hospitals in your region?
e.g., DFW
e.g., DFW
robdobyns said:
In 2-3 weeks a monoclonal antibody RCT study using Leronlimab
Will be unblinded. This drug might have promise.
This is a favorite pump and dump stonk. On the stonk boards they call this drug "Lemonaid"
I have been extremely skeptical that there is something fishy going on with this thing. Prior to Covid they were seeking funding to use this to treat HIV, and people were pumping the stock based on that.
Then magically, Covid came along and they were like, yeah it's a COV drug now, trust us.
If Lemonaid works that's great, but it seems like a giant scam to me.
CYDY is the stock ticker, it's OTC ticker so most places don't cover it.
When I first saw this stock I thought the same as you. So I educated myself on the immunological issues seen in Covid.
The company looked fishy and the CEO did not inspire trust.
But there is a virologist/pathologist named Bruce Patterson who among other things was the Head of the Department of Virology at Stanford. He has a LAB company called InCellDX.
I listened to him on two webinars and a TedX talk.
He has drawn all the cytokine levels and RANTES levels on the 75 patients who were treated WITH Leronlimab under E IND. He said the lab results showed drastically lower cytokine and RANTES levels. These changes correlated with clinical improvement.
Also viral load was way down.
Clotting issues were much better.
And CD8 and CD5 ratios were returned to normal and the immune system was restored to normal functioning.
Cydy has finished a PHASE 3 study of 800 HIV Patients.
No side effects. Easy to administer. Covid patients get two injections sub-Q on day 1 and day 7.
Could be a real game changer.
The market has responded this week by an increase in Share price from 3.45 to 6.97
Company will be on the NYSE in July.
Not a pump and dump. But it did look like one in January.
The company looked fishy and the CEO did not inspire trust.
But there is a virologist/pathologist named Bruce Patterson who among other things was the Head of the Department of Virology at Stanford. He has a LAB company called InCellDX.
I listened to him on two webinars and a TedX talk.
He has drawn all the cytokine levels and RANTES levels on the 75 patients who were treated WITH Leronlimab under E IND. He said the lab results showed drastically lower cytokine and RANTES levels. These changes correlated with clinical improvement.
Also viral load was way down.
Clotting issues were much better.
And CD8 and CD5 ratios were returned to normal and the immune system was restored to normal functioning.
Cydy has finished a PHASE 3 study of 800 HIV Patients.
No side effects. Easy to administer. Covid patients get two injections sub-Q on day 1 and day 7.
Could be a real game changer.
The market has responded this week by an increase in Share price from 3.45 to 6.97
Company will be on the NYSE in July.
Not a pump and dump. But it did look like one in January.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
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