Pilot Study of Vitamin D in Hospitalized Patients

3,929 Views | 20 Replies | Last: 5 yr ago by BiochemAg97
Not a Bot
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AG
https://www.sciencedirect.com/science/article/pii/S0960076020302764

Looks like administering Vitamin D to hospitalized patients significantly reduced ICU status and death. Small trial in Spain.
kubiak03
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It's no secret getting outside is good for you and there was talk months ago that vitamin D helps a lot with these viruses.
Drip99
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kubiak03 said:

It's no secret getting outside is good for you and there was talk months ago that vitamin D helps a lot with these viruses.



Yeah I always tell the wife that my afternoon habit of laying around in the pool sipping Rita's all afternoon is good for me
FalconAg06
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Man 13 out of 26 to ICU? There had to be something different about that group, no?
Petrino1
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Ive had lingering covid symptoms for 3 months now. I took Zithromax and a steroid pack with no luck. Last week I started taking a multivitamin + extra Zinc, vitamin C/D, and B12. I'm already feeling better and can feel the symptoms minimizing. I don't know if it's due directly to the vitamins or if it's just naturally going away, but either way I'm all in with the vitamins helping! Certainly can't hurt taking them.
Bonfired
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I've been knocking back 15,000 IUs of vitamin D a day for the last few months, and had been doing 10,000 IUs a day for a year or so before that...had significant vitamin D deficiency at an annual physical.

Add in some of the supplements Doc Coates suggested, plus dropping a good chunk of weight, and at a minimum I feel like Covid wouldn't kick my ass too badly if I got it. Putting up as much of a wall as I can.
Gizzards
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Bonfired said:

I've been knocking back 15,000 IUs of vitamin D a day for the last few months, and had been doing 10,000 IUs a day for a year or so before that...had significant vitamin D deficiency at an annual physical.

Add in some of the supplements Doc Coates suggested, plus dropping a good chunk of weight, and at a minimum I feel like Covid wouldn't kick my ass too badly if I got it. Putting up as much of a wall as I can.
Wow, that is way too much vitamin D and can lead to kidney issues especially stones. The covid studies only show that people who are deficient don't do so well. Having supratherapeutic levels has no health benefit.
OPAG
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This study would be at least one indicator that that this CV is not a respiratory disease but a blood vessel one.

https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63
"only one thing is important!"
Bonfired
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Gizzards said:

Bonfired said:

I've been knocking back 15,000 IUs of vitamin D a day for the last few months, and had been doing 10,000 IUs a day for a year or so before that...had significant vitamin D deficiency at an annual physical.

Add in some of the supplements Doc Coates suggested, plus dropping a good chunk of weight, and at a minimum I feel like Covid wouldn't kick my ass too badly if I got it. Putting up as much of a wall as I can.
Wow, that is way too much vitamin D and can lead to kidney issues especially stones. The covid studies only show that people who are deficient don't do so well. Having supratherapeutic levels have no health benefit.


To that end, I went and looked at my last panel from my annual screening (about 6 weeks ago)...Vitamin D levels were slightly above optimal (65.4 ng/mL) for the first time ever. My levels were pretty regularly in the 20s and 30s on that same scale in years past.

Toxicity is considered > 150 ng/mL, so I'll dial it back to more maintenance levels of supplementing.

Doc was not at all displeased and didn't think a thing of it when we were going through my results.
KidDoc
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Gizzards said:

Bonfired said:

I've been knocking back 15,000 IUs of vitamin D a day for the last few months, and had been doing 10,000 IUs a day for a year or so before that...had significant vitamin D deficiency at an annual physical.

Add in some of the supplements Doc Coates suggested, plus dropping a good chunk of weight, and at a minimum I feel like Covid wouldn't kick my ass too badly if I got it. Putting up as much of a wall as I can.
Wow, that is way too much vitamin D and can lead to kidney issues especially stones. The covid studies only show that people who are deficient don't do so well. Having supratherapeutic levels has no health benefit.
This is not true- taking too much calcium can cause kidney stones but vitamin D does not increase your risk of kidney stones at all. The side effects of overdosing on Vitamin D are very mild- fatigue, headache, stomach ache, weakness.

Most docs don't care if people want to take megadoses of vitamins because they are generally benign outside of calcium and Vitamin A.

Is it helpful? Not likely. But if you feel like you want to try megavitamins it is your money to burn.

(I'm on 2500 IU/day of Vitamin D in my multivitamin)

No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Gizzards
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Actually, it does as it leads to hypercalcemia and subsequent hypercalciuria. I'm a urologist and have treated plenty of patients that fall into this category.
KidDoc
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Gizzards said:

Actually, it does as it leads to hypercalcemia and subsequent hypercalciuria. I'm a urologist and have treated plenty of patients that fall into this category.
I could see that relationship! Excellent point.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Tailgate88
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Gizzards said:

Actually, it does as it leads to hypercalcemia and subsequent hypercalciuria. I'm a urologist and have treated plenty of patients that fall into this category.
Username sort-of checks out?
74OA
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The Mayo Clinic lists kidney damage among the potential issues for those taking more than 4000IU a day: Vit D
goodAg80
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Quote:

The side effects of overdosing on Vitamin D are very mild- fatigue, headache, stomach ache, weakness.

And pregnancy. You forgot that.
Maybe Next Year
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I don't get it?
ramblin_ag02
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Gizzards said:

Actually, it does as it leads to hypercalcemia and subsequent hypercalciuria. I'm a urologist and have treated plenty of patients that fall into this category.
I thought this sounded a bit off. So I went down a rabbit hole.

Here's a few studies and reviews about it.

https://academic.oup.com/ajcn/article-abstract/109/6/1578/5475743?redirectedFrom=fulltext

https://www.sciencedirect.com/science/article/abs/pii/S009042952030114X

https://bjui-journals.onlinelibrary.wiley.com/doi/full/10.1111/bju.14658

https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000200340

Seems like it one of those things where everyone thinks it's true but no one has any proof. So far even large populations studies have found no increased stones among people supplementing low or high dose Vit D and calciuric stone patients are more likely to have low vitamin D levels than high.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Charpie
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I think I'll keep listening to my doctor about these things.
BlackGoldAg2011
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Maybe Next Year said:

I don't get it?
"Vitamin D" is a euphemism in this use
Cepe
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I also take Vit K2 to help with the calcification. Calcium, Vit D3, and Vit K2 work together to put the calcium where it belongs. . .

Lots of information about it, but here's a quick one. . .

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613455/
Quote:

Animal and human studies suggest that optimal concentrations of both vitamin D and vitamin K are beneficial for bone and cardiovascular health as supported by genetic, molecular, cellular, and human studies.
It's important to note this is K2, not K1, which is for clotting. Two totally different things.
Maybe Next Year
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For???
BiochemAg97
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Fun fact...

Vit D (cholecalciferol) is used as a rat poison. Obviously, much higher doses (mg/kg) than your daily supplement.
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