for those in the know on vaccine mfg....

Aggie95

Joined: Oct 11, 1999

Posts: 33,150

User Profile

Private Message

Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

10:36a, 11/18/20

AG

they say approximately 20 million doses by end of the year. Is the process to make the vaccine that long? Do certain components of the vaccine have to cure over time? If the gov't gave another huge influx of cash could they make more?

I know we are crazy in debt, but I would rather see $1T go to this process than another $2T stimulus.....but that point is moot if the process truly can't be sped up.

Please tell me there's a special place in Heaven for Aggie fans! It's like we are living some sort of penance on Earth.

Harry Stone

Joined: Feb 26, 2007

Posts: 39,343

User Profile

Private Message

Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

5:07p, 11/18/20

AG

The mRNA vaccines dont have to cure over time like traditional vaccines. But we also don't have the manufacturing power to produce. Even though they are beginning with 4,000 gms of mRNA, which sounds like so little, we've never really even produced 100 gms in such a short time in this world. Once the first 20M or so doses are produced, the mfg process will inevitably speed up, but right now we r teaching a newborn how to crawl at 1 month, so to speak.

5

amercer

Joined: Apr 25, 2003

Posts: 30,306

User Profile Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

7:51p, 11/18/20

AG

There is only so much bio manufacturing capacity in the world and it can be very specific for the molecules they are making. Also, even at warp speed there are QA and regulatory things you just can't skip without putting lives in danger.

3

Leggo My Elko

Joined: Nov 11, 2010

Posts: 3,870

User Profile Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

1:50p, 11/19/20

AG

What about distribution? I understand the Pfizer vaccine has to be kept at -80 Celsius, not sure about the Moderna.

If it has to be kept at -80C, how much of the normal distribution channels does that eliminate?

CDub06

Joined: Nov 22, 2003

Posts: 64,310

User Profile Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

In reply to Leggo My Elko • 2:21p, 11/19/20

AG

Pfizer's has to be stored at -70c. Moderna's stays stable under normal refrigeration, so it doesn't require any special equipment.

Detmersdislocatedshoulder

Joined: Mar 30, 2020

Posts: 15,330

User Profile Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

3:22p, 11/19/20

Why do these vaccines have to be stored at -70 to -80 degrees? Is that normal for most vaccines?

2

rkramer

Joined: Nov 28, 2010

Posts: 3,165

User Profile Ignore User Stop Ignoring

How long do you want to ignore this user?

24 hours One week Permanently Cancel

11:44p, 11/19/20

AG

mRNA (which these vaccines are based on) is inherently unstable and must be stored at very low temperatures to maintain stability. There are work arounds with different formulations that can achieve stability at higher temperatures, but these take time to develop.

Moderna has been working on more stable mRNA vaccine formulations long before the pandemic, which is why their's can be stored under normal refrigerated conditions.