I said "high risk individuals" (i.e. old, and weakened immune people who typically have a lower degree of side effects from the current vaccines). The boosters will probably be ratcheted down as we better understand required dosing levels. Add in that we are developing treatments that are actually proving to be effective (monoclonal antibodies, protease inhibitors, etc) and the pool "high risk individuals" will get smaller and smaller.

KidDoc said:

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Mostly due to the fact that there has not been a single dose vaccine with any long term efficacy in the last 20 years. Our immune system really seems to need that 2nd exposure.

So it is not the mRNA tech that I think favors long term immunity, but the 2 exposures.

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I'm mainly concerned for the short term at the moment.

I got the Johnson and Johnson vaccine on Wednesday with no side effects at all. Since when I had it last May, it was so mild, I'm not going to worry too much about it. My main concern is not to get it and give it to someone else who might not have such a mild case.

I figure that we're basically in a learning curve and we are all, basically guinea pigs.

As far as one dose, how about the measles vaccine? Is that one dose or two? I've never had measles and I don't know if I ever had a measles vaccine, but if I did, it was an early vaccine in the mid 60s and I've never had any kind of booster.

Measles is at age 1 and age 4-6.

Birth-18 Years Immunization Schedule | CDC

KidDoc said:

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Measles is at age 1 and age 4-6.

Birth-18 Years Immunization Schedule | CDC

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They didn't have a measles vaccine when I was that young.

If I got it at all, it was almost surely when I was in junior high or high school when my younger brother got the measles or when I got my physical to attend A&M. I don't know if A&M required the vaccine back then.

TAMUallen said:

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How the hell do they determine where these go?

Big Lake, TX, with a population of less than 3,000 had 300 j&j vaccines on Saturday

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but a hot bed of O&G activity....

Also a shot in the dark but with less storage and dose tracking requirements it makes sense for J&J to go to more remote spots

Very good point

KidDoc said:

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Why are you seeking a shot with 65% efficacy vs 95% ? I'm just curious not judging.

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Really doc? Can't think of a key differentiator?