Both Christopher Reeve and Henry Cavill worked well for Superman
Michael Keaton as Batman was initially a WTF casting that I believe worked out much better than anticipated
Harrison Ford as both Han Solo and Henry Jones Jr
Chris Hemsworth as Thor, Chris Evans as Captain America, Robert Downy Jr as Iron Man
In a difficult cast to assemble, the rebooted Star Trek cast, especially Chris Pine as Kirk and Karl Urban as McCoy (I say difficult because the original cast is so well known)
Alan Rickman as Hans Gruber
Arnold Schwarzenegger as the Terminator
John Belushi as Wild Bill Kelso (P-40 fighter pilot) in 1941 and John Blutarsky in Animal House
Ian McDiarmid as Senator/Emperor Sheev Palpatine
Michael Keaton as Batman was initially a WTF casting that I believe worked out much better than anticipated
Harrison Ford as both Han Solo and Henry Jones Jr
Chris Hemsworth as Thor, Chris Evans as Captain America, Robert Downy Jr as Iron Man
In a difficult cast to assemble, the rebooted Star Trek cast, especially Chris Pine as Kirk and Karl Urban as McCoy (I say difficult because the original cast is so well known)
Alan Rickman as Hans Gruber
Arnold Schwarzenegger as the Terminator
John Belushi as Wild Bill Kelso (P-40 fighter pilot) in 1941 and John Blutarsky in Animal House
Ian McDiarmid as Senator/Emperor Sheev Palpatine