Thanks, I wonder where the millions of doses we received went?barnyard1996 said:
Sending this link as not an answer but as a data point for discussion.
https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Hydroxychloroquine%20Sulfate%20Tablets&st=c
Hydroxychloroquine...........
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1854 Replies |
Last: 7 mo ago by Jabin
I wonder too. I can only speculate the supply chain is being kept under wraps for the time being. People that are talking don't know, and people that know aren't talking.
If only there was this video posting website where the high priests of proper mask don/doff procedures could show the unwashed how it's done
74Ag1 said:
https://nypost.com/2020/04/04/long-island-doctor-tries-new-hydroxychloroquine-for-covid-19-patients/
I think there was a doc on here who mentioned doxycycline an alternative. Great to hear about this, I know it's anecdotal but seeing that success in such an old and comorbid cohort is heartening.
74Ag1 said:
https://nypost.com/2020/04/04/long-island-doctor-tries-new-hydroxychloroquine-for-covid-19-patients/
Seems to be pretty significant if the numbers are correct. I've heard 80% mild cases, but of those 1/4 will have to be hospitalized, which I would assume is higher in the population that he was treating, of his patients only 14% had to be hospitalized, with a mortality rate of 4.2%, which I think is still great for their age and status
One of 2 recommended therapeutic treatment options from CDC
https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic-options.html
https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic-options.html
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"A National Institutes of Health (NIH)-sponsored adaptive double-blinded, placebo-controlled trial of remdesivir versus placebo in COVID-19 patients with pneumonia and hypoxia is enrolling non-pregnant persons aged 18 years and older with oxygen saturation of 94% on room air or requiring supplemental oxygen or mechanical ventilation"
I'd sure hate to draw the short straw and get a placebo.
I'd sure hate to draw the short straw and get a placebo.
Double blinded, so your healthcare provider will also not know if you got the placebo.
Infection_Ag11 said:aggie-beta said:
I don't like Fauci either.
I don't have a quote on him but he is helping drive the policy to lie to the American public about wearing masks. They knew that masks, if properly worn, would help reduce the spread and lied to us all like we were little kids that didn't deserve the truth. They could have said there is a shortage so try these other options instead of medical grade masks and it would have spread a lot less than it has.
Now he acts like a medicine that many doctors believe in should not be widely used until the pandemic is over and the bodies are piled up.
F him.
He didn't lie to anyone, most people just fail to grasp the nuance.
Masks don't protect you, they protect everyone else FROM you (if worn properly, which most people don't do). If everyone (ie 80-90% of the population) wears masks correctly all day long, it has benefit in reducing disease transmission by so substantially decreasing the environmental virus burden that it has trouble spreading.
It is 100% accurate to say wearing a mask to Walmart does not decrease your chances of contracting the virus.
Masks also protect you from yourself. We touch our face 20+ times per hour. If folks are not washing hands enough, they can get the virus from hands to the face touching. Masks will decrease that type of transmission.
Can we produce this domestically? India just banned all exports.
https://www.bloomberg.com/news/articles/2020-04-05/india-bans-all-exports-of-trump-s-game-changer-virus-drug?srnd=premium
https://www.bloomberg.com/news/articles/2020-04-05/india-bans-all-exports-of-trump-s-game-changer-virus-drug?srnd=premium
Didn't Trump announce that India was going to supply some of this stuff to the US? I could have misunderstood him during his PC yesterday but I remember him talking about India.flyingaggie12 said:
Can we produce this domestically? India just banned all exports.
https://www.bloomberg.com/news/articles/2020-04-05/india-bans-all-exports-of-trump-s-game-changer-virus-drug?srnd=premium
India has issued HCQ as a prime treatment protocol and banned all exporting of the drug.
Do you others keep expecting the rate of increase in the number of confirmed cases to start outpacing the increase in deaths like me and it never happens?
I guess I am just optimistic by nature and I keep thinking we are the USA and we will figure out how to keep this from killing people better than other places.
I thought when this HCQ treatment started being used it would make a huge impact in deaths and I am not seeing it, but I'm also just taking a quick look day to day and not analyzing the numbers. Does anyone else see a positive trend?
I guess I am just optimistic by nature and I keep thinking we are the USA and we will figure out how to keep this from killing people better than other places.
I thought when this HCQ treatment started being used it would make a huge impact in deaths and I am not seeing it, but I'm also just taking a quick look day to day and not analyzing the numbers. Does anyone else see a positive trend?
My suspicion is we're largely waiting until too late in the course of the disease in a patient to intervene with HCQ.
Based on the hypothesized mechanism, it's not likely to be effective once a patient requires hospitalization.
Based on the hypothesized mechanism, it's not likely to be effective once a patient requires hospitalization.
Faster tests will help greatly.
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barnyard1996 said:
Faster tests will help greatly.
Or getting more of the medical community to stop relying solely on a test with ~30% false negatives before treating people with fairly obvious Covid-19.
High fever, body aches, shortness of breath, etc, I'd contend it's fairly ridiculous to wait on a test result before getting someone on treatment.
HCQ isn't exactly harmless
it might seem like Tamiflu but it isn't
it might seem like Tamiflu but it isn't
Thats why we let doctors make the call with their patient.cone said:
HCQ isn't exactly harmless
it might seem like Tamiflu but it isn't
Keegan99 said:
My suspicion is we're largely waiting until too late in the course of the disease in a patient to intervene with HCQ.
Based on the hypothesized mechanism, it's not likely to be effective once a patient requires hospitalization.
Yeah, I don't get this. Waiting too late is like expecting a pain killer to regrow a limb that's been amputated.
Infection_Ag11 said:aggie-beta said:
I don't like Fauci either.
I don't have a quote on him but he is helping drive the policy to lie to the American public about wearing masks. They knew that masks, if properly worn, would help reduce the spread and lied to us all like we were little kids that didn't deserve the truth. They could have said there is a shortage so try these other options instead of medical grade masks and it would have spread a lot less than it has.
Now he acts like a medicine that many doctors believe in should not be widely used until the pandemic is over and the bodies are piled up.
F him.
He didn't lie to anyone, most people just fail to grasp the nuance.
Masks don't protect you, they protect everyone else FROM you (if worn properly, which most people don't do). If everyone (ie 80-90% of the population) wears masks correctly all day long, it has benefit in reducing disease transmission by so substantially decreasing the environmental virus burden that it has trouble spreading.
It is 100% accurate to say wearing a mask to Walmart does not decrease your chances of contracting the virus.
This is absolutely maddening. We are shutting down the economy and taking away people's jobs to slow the spread. Masks slow the spread and you cannot deny that. Fauci and the CDC live in a bubble and are completely out of touch with reality for the average American.
Philip J Fry said:Infection_Ag11 said:aggie-beta said:
I don't like Fauci either.
I don't have a quote on him but he is helping drive the policy to lie to the American public about wearing masks. They knew that masks, if properly worn, would help reduce the spread and lied to us all like we were little kids that didn't deserve the truth. They could have said there is a shortage so try these other options instead of medical grade masks and it would have spread a lot less than it has.
Now he acts like a medicine that many doctors believe in should not be widely used until the pandemic is over and the bodies are piled up.
F him.
He didn't lie to anyone, most people just fail to grasp the nuance.
Masks don't protect you, they protect everyone else FROM you (if worn properly, which most people don't do). If everyone (ie 80-90% of the population) wears masks correctly all day long, it has benefit in reducing disease transmission by so substantially decreasing the environmental virus burden that it has trouble spreading.
It is 100% accurate to say wearing a mask to Walmart does not decrease your chances of contracting the virus.
This is absolutely maddening. We are shutting down the economy and taking away people's jobs to slow the spread. Masks slow the spread and you cannot deny that. Fauci and the CDC live in a bubble and are completely out of touch with reality for the average American.
I'll table further discussion about this to keep the thread on track.
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went to Home Depot and a garden center today
mask usage is probably at 40%
80% of employees were masked. that's where the preference cascade will start
mask usage is probably at 40%
80% of employees were masked. that's where the preference cascade will start
I absolutely see the new normal where businesses ask for those that shop to please wear a mask for the protection of their employees
there are nudges everywhere to get mask usage up
there are nudges everywhere to get mask usage up
Because we don't have enough testing or supply of the drug (assuming effectiveness).Philip J Fry said:Keegan99 said:
My suspicion is we're largely waiting until too late in the course of the disease in a patient to intervene with HCQ.
Based on the hypothesized mechanism, it's not likely to be effective once a patient requires hospitalization.
Yeah, I don't get this. Waiting too late is like expecting a pain killer to regrow a limb that's been amputated.
We don't know if someone has the condition early in order to give it to them because we can't test quickly enough, and if we did there isn't enough to go around.
It is also helping people with more severe symptoms as well. According to what I have read, but sooner the better for sure.
My prediction is the RCT will show no significant benefit or minimal benefit due to when therapy is started (meaning too late in the course) and more severely infected patients. I am currently treating potentially higher risk patients with suspected disease early and not waiting for the test after ruling out (flu, strep, other respiratory pathogens) possible causes. It's a very small number thus far but you can't convince me it's not the appropriate thing to do at this point.
That seems to the opposite of everything we're hearing actually.DadHammer said:
It is also helping people with more severe symptoms as well. According to what I have read, but sooner the better for sure.
I read where India banned the export of HCQ. What is the supply situation like for that in the US?
Is it/can it be made here if current supplies are not enough?
Is it/can it be made here if current supplies are not enough?
It helps early better, but it is still helpful with sicker patients. Have read lots of reports on this.
what are the risks then?cone said:
HCQ isn't exactly harmless
it might seem like Tamiflu but it isn't
highly highly doubt it. Old habits die hard.cone said:
I absolutely see the new normal where businesses ask for those that shop to please wear a mask for the protection of their employees
there are nudges everywhere to get mask usage up
I agree. I think we will look back on this and find that Fauci has done more harm than good. Good guy. Bad at making policy.
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