If you can ignore the liberal agenda (???WHY???) of the reporter, wonderful news. One death and three hospitalizations among 56 nursing home positives? Incredible results.DadHammer said:
More good news.
https://www.houstonchronicle.com/news/houston-texas/houston/article/texas-city-nursing-home-doctor-unproven-drug-trump-15192584.php
Psst...WRONG FORUM.DadHammer said:
I know, the liberals have become evil. Cheering for death.
DadHammer said:
I know, the liberals have become evil. Cheering for death.
When it has a controlled study.74Ag1 said:
When does an unproven drug that works become proven?
a) Don't really care for many reasons. I probably shouldn't have said anything anyway but some people on here are maddening.buffalo chip said:Psst... I could debate your point, but the WRONG FORUM police are out in droves... WATCH OUT!fig96 said:Psst...WRONG FORUM.DadHammer said:
I know, the liberals have become evil. Cheering for death.
Also, that article is incredibly fairly written, it simply mentions the drug isn't proven and that they need to discuss that with patients. If that's a "liberal agenda" and "cheering for death" then geez.
Marcus Aurelius said:
FYI. A study of 63 pts at Henry Ford hospital has been submitted to NEJM. Publication pending. Not a RPCT. 63 pts. 32 received HCQ. 31 did not. These pts were on avg admitted for dyspnea around day 7. Findings. No improvement in survival, N/L ratio. HCQ pts also had statistically significant increased need for respiratory support. Take it FWIW.
Marcus Aurelius said:
FYI. A study of 63 pts at Henry Ford hospital has been submitted to NEJM. Publication pending. Not a RPCT. 63 pts. 32 received HCQ. 31 did not. These pts were on avg admitted for dyspnea around day 7. Findings. No improvement in survival, N/L ratio. HCQ pts also had statistically significant increased need for respiratory support. Take it FWIW. Anecdotally I have seen similar results once these pts are very sick. Didnt expect negative effects on respiratory outcomes however. Jury still out.
Marcus Aurelius said:
No
k2aggie07 said:
Another preprint
https://www.medrxiv.org/content/10.1101/2020.04.07.20056424v1.full.pdf
High dose vs low dose HCL with all pts receiving azithromycin also.
No positive observed mortality effect yet.
Had to stop high dose recruitment due to cardiovascular events and trend toward higher lethality than low dose.
I think with it's proposed primary mechanism of action being inhibiting viral replication. I am expecting no benefit if started after patients are severe enough to require hospitalization since by that time they likely have way too much virus in their system. I think it will have to be used similar to Tamiflu early in the process and hopefully decrease hospitalizations and ICU admissions. While Tamiflu doesn't inhibit viral replication it inhibits budding of the virus so a similar concept. I believe if we in primary care use it on patients with a high index of suspicion and who have risk factors will likely see benefits but very doubtful if implemented late as too much virus is already been made.Marcus Aurelius said:
FYI. A study of 63 pts at Henry Ford hospital has been submitted to NEJM. Publication pending. Not a RPCT. 63 pts. 32 received HCQ. 31 did not. These pts were on avg admitted for dyspnea around day 7. Findings. No improvement in survival, N/L ratio. HCQ pts also had statistically significant increased need for respiratory support. Take it FWIW. Anecdotally I have seen similar results once these pts are very sick. Didnt expect negative effects on respiratory outcomes however. Jury still out.
Right now, other than 'maybe' giving them a test that they have to wait about a week for results for, it appears that for the most part it's "Go home, and good luck"aggiegolfer03 said:
So what is being done for patients who show enough symptoms to present a flu like illness, enough that they'd normally end up at their family doctor?
Because as you said, I would think THAT would be the time for seeing improved outcomes from HCL treatment.
Oh that is horrible news! I will pray for him, you and your family!benchmark said:
You can add my uncle to the list of those who received the drug combo but didn't survive. Probably given too late to be of help. Hospital day 25, Vent day 22.
Reveille said:Oh that is horrible news! I will pray for him, you and your family!benchmark said:
You can add my uncle to the list of those who received the drug combo but didn't survive. Probably given too late to be of help. Hospital day 25, Vent day 22.
DadHammer said:
Another positive report. Man I hope this really works to save people and get us on a path back to work quickly.
https://www.wtvm.com/2020/04/06/patients-recovering-covid-phoebe-putney-memorial-hospital-albany/
