No serious illness or death from those vaccinated who did get the COVID. I bet this will become the vaccine for the healthy adult.

Compared to the other options, this seems awful.

If you're 85 yes.

If you're young and healthy I think it's a great option to help lesson the load of covid for the hospitals.

Granted, not many young healthy people go to the hospital for covid, but I think this takes that number almost to zero for that demographic.

I'd take this one.

So more effective than the flu vaccine. With this vaccine and no risk factors it seems like a viable option for healthy people.

Keep in mind, that's for a single dose of J&J. They are currently doing a study for a two-dose regimen. The efficacy may be higher for that.

ORAggieFan said:

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Compared to the other options, this seems awful.

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95% was a home run, the goal at the start was 50%. It shows you how lucky and how great the mRNA tech is to get 95%.

I think the new technology is awesome, and is perfect for older people/an at risk population.

But then there is a demographic of young healthy people who are reluctant to get the new shot right away as compared to the traditional type.

Reason for this is questions about potential long term health complications/fertility. I was supposed to take the moderna vaccine during the trial process and opted out because I had to have protected sex for up to three-six months.

Will the vaccine make me infertile? Probably not, but at my age I don't want to risk it because I'm just now starting my family.

Don't forget this also helps a large supply chain issue. J&J is the easiest to distribute of the two we have now, requiring one dose and only standard refrigeration.

Hit the young crowd as others said and leave the other two to the elderly.

Something else to think about, I think we need to start viewing this from a limiting severe covid perspective.

We might not eradicate it, but I bet we can vaccinate our way to eliminate the hospitalization issue.

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Compared to the other options, this seems awful.

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I read this and think of that great Louis C.K. monologue.



Given the backdrop, If the trial shows 0% of participants went to the hospital or died than we have found a really great treatment.

Considering where we were at a year ago this seems like a win. 72% effective rate within the US with what appears to be heavy protection against sever cases.

1 dose, easy to distribute and J&J scale behind it. The mRna tech is getting us there. I think the J&J shot and similar will win the war globally.

I wish this one wasn't developed using a fetal stem cell line.

Starting to hear from people I know who are having severe reactions to the 2nd shot. Not hospitalized but sick for several days. I think Marcus Aurelius had some pretty severe side effects as well.

If there is a vaccine that doesn't have severe side effects, I can imagine that will be preferred unless you are very high risk and need the extra protection.

I'm not looking forward to the Pfizer or Moderna shot based on what I'm hearing.

The J&J shot completely eliminated severe disease, even in the new stains. That is both incredible, and all we need.

In a head to head trial against the South African variant J&J might be better than the mRNA vaccines. They didn't do the trials so we don't know.

Shots in arms is what we need ASAP to get us to normalcy and eliminate unnecessary deaths. The Pfizer and Moderna have been the first out the gates and it sounds like J&J, Novavax and maybe Astra Zeneca are the reserves. While not as high efficacy against the "normal" COVID 19 strain, these 3 are promising because they add a needed influx of available doses and still do a dang good job (remember anything above 50 to 60% is considered bonus). The fact that those who do get COVID19 after the immunizations do not develop significant disease that requires hospitalization is incredibly encouraging. Better days are on the way!

Too much focus on the shortcomings of the vaccines and potential fears and not enough optimism about what they've already proven they can do, even against variants.

I think what some people are trying to do is to scare people to keep them vigilant, but I think that has the opposite effect. If people feel like the adjusted behavior required to keep the virus low has no end in sight, then they're much less likely to adopt that behavior.

If people feel like they only have to buckle down for a few more months until they've gotten a vaccine, it becomes much more palatable.

Get the vaccine. It will greatly reduce your odds of getting infected and virtually eliminate your chances of having a severe outcome from the disease.

The lower we can keep the cases in the mean time, the less opportunity these new variants have to arise and to spread.

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I think what some people are trying to do is to scare people to keep them vigilant, but I think that has the opposite effect. If people feel like the adjusted behavior required to keep the virus low has no end in sight, then they're much less likely to adopt that behavior.

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There was a really excellent article in the Atlantic on the incredibly failed messaging regarding having to keep hunkering down after getting the vaccine. It is essentially removed the carrot from global society.

https://www.theatlantic.com/ideas/archive/2021/01/giving-people-more-freedom-whole-point-vaccines/617829/

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Vaccinated People Are Going to Hug Each Other
The vaccines are phenomenal. Belaboring their imperfectionsand telling people who receive them never to let down their guardcarries its own risks.
JANUARY 27, 2021

When Americans began receiving coronavirus vaccines last month, people started fantasizing about the first thing they'd do when the pandemic ends: go back to work, visit family, hug friends. But the public discussion soon shifted. One news article after another warned about everything that could go wrong: Protection isn't immediate; vaccinated people can still transmit the virus; vaccinated people might get mild infections that could become chronic; vaccines might not work as well against new coronavirus variants. "COVID-19 Vaccine Doesn't Mean You Can Party Like It's 1999," one headline admonished. Can vaccinated people at least hang out with one another? Nope, masks and distancing are still required. "Bottom line," another article concluded ominously: "You will need to wear a face mask after you're vaccinated until COVID-19 cases become nearly nonexistent."

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Immubiology professor from Yale:

We have let perfect become the enemy of good. There is no 100% guarantee in anything in life. How did we get here as a society?

That we have these vaccines already (supply/distribution bugs notwithstanding) is a miracle. That all of them are so good and robust, as posts show above (and better than any flu vaccine) is even more amazing. But the picking them apart for whatever reason, and the media infatuation with doing so instead of promoting is killing it and bringing more despair.

We are our own worst enemy.

HotardAg07 said:

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Immubiology professor from Yale:

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So what gives? That sounds like a home run and very much more encouraging than 66%, which is still good news

SouthTex99 said:

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As I recall overall efficacy for the MRNA vaccines after 1 shot wasn't much better than J & J...maybe worse. I wonder how effective a 2 dose J & J regimen would be?

All else equal, or close to equal, I'd pick J & J. There's still a lot we don't know about MRNA vaccines.

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We know they are very effective and safe. Was there another question?

I'm far from an anti-vaxxer but we KNOW it? The first vaccines of their kind are given emergency approval and we KNOW it?

hoosierAG said:

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We have let perfect become the enemy of good. There is no 100% guarantee in anything in life. How did we get here as a society?

That we have these vaccines already (supply/distribution bugs notwithstanding) is a miracle. That all of them are so good and robust, as posts show above (and better than any flu vaccine) is even more amazing. But the picking them apart for whatever reason, and the media infatuation with doing so instead of promoting is killing it and bringing more despair.

We are our own worst enemy.

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Well, for starters, we created incredible numbers of online and media forums dedicated to talking about nothing but a virus...

When is it being presented and how long until this one is being given? Another month?

This guy gets it, one of you??

GAC06 said:

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I'm far from an anti-vaxxer but we KNOW it? The first vaccines of their kind are given emergency approval and we KNOW it?

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mRNA vaccines aren't new. They are new for human distribution.

Was driving from Laredo back to Houston today and listening to NPR, they had J&J's chief scientist on. His attitude was all pharma companies need to work together and just get people vaccinated. He said the J&J vaccine about 60 something percent efficiency at preventing disease and 100% efficient at preventing hospitalization and death, can manufacture billions of doses in a short time and doesn't require much special handling. They are applying to FDA for emergency approval early next week. He said it was effect against the variants. So my take away was this vaccine has a 60% chance of preventing disease all together and even if you do get sick 100% effective at keeping people from needing hospitalization and 100% effective at preventing death. Their study was huge and in various countries and regions. In my book that is a big win! I like that he had nothing bad to say about tbe other vaccines and just said no matter what just need to get people vaccinated. I'd take it!! I can remember exactly but I think he said no major side effects

MarylandAG said:

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Was driving from Laredo back to Houston today and listening to NPR, they had J&J's chief scientist on. His attitude was all pharma companies need to work together and just get people vaccinated. He said the J&J vaccine about 60 something percent efficiency at preventing disease and 100% efficient at preventing hospitalization and death, can manufacture billions of doses in a short time and doesn't require much special handling. They are applying to FDA for emergency approval early next week. He said it was effect against the variants. So my take away was this vaccine has a 60% chance of preventing disease all together and even if you do get sick 100% effective at keeping people from needing hospitalization and 100% effective at preventing death. Their study was huge and in various countries and regions. In my book that is a big win! I like that he had nothing bad to say about tbe other vaccines and just said no matter what just need to get people vaccinated. I'd take it!! I can remember exactly but I think he said no major side effects

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That is great news and great messaging. Epidemic inoculation is all about layering in levels of protection as fast as possible. This is what Salk did.

The most important metrics here are speed to market and logistical ease.

This one will be the game changer.

It's pretty wild that we wanted 50% and this one is getting shunned by so many because it's not as high as the Phizer and Moderna. If those 2 never came around people would be jumping through hoops to get the J&J ASAP